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PREDICTORS BILIARY TRACT TOXICITY
• Retrospective 96 liver patients
• Median dose 40Gy in 5 fractions (25-54Gy in 1-5 fractions)
• CCA:
- biliary obstruction/stricture
- hepatobiliary infections
• Toxicity associated with SBRT dose-parameters
• V BED10 72Gy< 21cc V BED10 66Gy< 24cc
Osmudson EC. Predictors of toxicity associated with SBRT to the central hepatobiliary tract.
IJROBP 2014