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Perfusion MRI

= Dynamic contrast susceptibility imaging

Transient signal loss by intravascular CM

T2*w Perfusion MRT

T2*-weighted MRI

Signal (a.u.)

40,0000

72,5000

105,0000

137,5000

170,0000

t (s)

0,0000 26,2500 52,5000 78,7500 105,0000

Diffusion

Diffusion MRI: How it works

First gradient field induces dephasing

»

Signal loss

Inverted gradient field induces

rephasing

»

Restoration of signal

Effect:

Stationary protons:

»

Return into phase and regain signal

Moving protons

»

Incomplete restoration of signal

»

Persistant signal loss

First Gradient: Dephasing

Second gradient: Rephasing

Stationary protons