General Analytical Needs
•
Infectious dose for humans 10‐100
organisms
•
Diagnostic testing via PCR
–
To date, no real time PCR for VEE
published
•
Need to include Subtypes IAB and IC
•
Ideal to exclude other Subtypes and
serotypes (ID, IE, IF, II, III, IV, V)
•
Need to distinguish EEE, WEE, VEE
VEEV is an Overlap Select Agent
USDA/HHS Regulations
•
Includes VEEV Subtypes IAB and IC only
•
Any subtypes of Venezuelan equine encephalitis
virus except for Subtypes IAB or IC are excluded
from Select Agent status provided that the
,
individual or entity can verify that the agent is
within the exclusion category.
–
TC‐83 vaccine strain and vaccine candidate strain
V3526 are excluded from Select Agent Regulations
