Fitness for Purpose (proposal)
Id tifi ti
f VEEV i
i
t l
en ca on o
n env ronmen a
samples
The method must be able to identify VEEV RNA
resulting from aerosol, solid or liquid samples.
Ideally, the method should include only epizootic
VEEV (Subtypes 1AB, 1C) and should exclude all
other VEEV. The limit of detection must be lower
than one infectious human dose of VEE.
Fitness for Purpose (proposal)
Id tifi ti
f VEEV i
i
t l
en ca on o
n env ronmen a
samples
The useable matrices for the PCR test (aerosol
collections, environmental swabs, air filters, etc.)
are defined with respect to their complexity,
presence of organic material and inorganic
material, and the expected duration of detectable
alphavirus RNA by PCR.
