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FOR EXPERT REVIEW PANEL USE ONLY
NOT FOR DISTRIBUTION
1
Expert Review Panel for Infant Formula and Adult Nutrition
Evaluation of Method MET -01/03 AOAC 2011.14
Title:
Determination of Ca, Cu, Fe, Mg, Mn, P, K, Na and Zn by ICP-AES in Infant Formula and Adult
Nutritionals
Author:
Hans Cruijsen, FrieslandCampina
Eric Poitevin, Nestle
Summary of Method:
Microwave digestion, ICP-AES determination
Method Scope/Applicability:
•
SPIFAN Matrices
•
Does not work reliably at the low end of the concentration range specified in the SMPR.
•
The performance with the SPIFAN Placebo samples and the IDF dairy samples did not meet the
RSDR specification in the SMPR for Cu, Mn, Fe and Zn.
General comments about the method:
•
Good method. Great multi-lab trial. The low end of the concentration range specified in the SMPR
is too optimistic for the ICP-AES technique for Cu, Mn, Fe and Zn. The Reproducibility RSD shows
this clearly with values as high as 56%.
Method Clarity:
Method Safety Concerns: