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1/03/2016

14

Relevant radiobiological factors

Technique: stereotactic ablative radiotherapy

27

Murai Radiat Oncol 2012 189 pts

Radiation pneumonitis - 3 months after resolution: organizing pneumonitis – 5 mg prednison

Relevant radiobiological factors

Total radiation dose

28

Guckenberger Radiother Oncol 2010 59 pts

Dose-response

relationship for

radiation-induced

pneumonitis (RP)

after pulmonary

stereotactic body

radiotherapy

Average MLD 10.3±5.6Gy

MLD Pts with RP12.5±4.3Gy > MLD pts without RP MLD 9.9±5.8Gy

59 patients