1/03/2016
14
Relevant radiobiological factors
•
Technique: stereotactic ablative radiotherapy
27
Murai Radiat Oncol 2012 189 pts
Radiation pneumonitis - 3 months after resolution: organizing pneumonitis – 5 mg prednison
Relevant radiobiological factors
•
Total radiation dose
28
Guckenberger Radiother Oncol 2010 59 pts
Dose-response
relationship for
radiation-induced
pneumonitis (RP)
after pulmonary
stereotactic body
radiotherapy
Average MLD 10.3±5.6Gy
MLD Pts with RP12.5±4.3Gy > MLD pts without RP MLD 9.9±5.8Gy
59 patients