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1/03/2016

15

Relevant radiobiological factors

Irradiated volume with SBRT

29

Dunlap Int J Radiat Oncol 2010 60 pts

Chest wall volume receiving >30Gy predicts risk of severe pain

and/or rib fracture after lung SBRT

60 patients

Robertson et al., Int J Rad Onc Biol Phys 2008

Better modeling of preoperative patients

Revised parameters

Previous parameters

Small bowel toxicity

• Acute small bowel toxicity depends on irradiated volume

96 patients