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J
IANMING
T
AO
460 Budding Ridge Road, CT 06410
Phone: 610.996.4173
Email:
jtao@spectrixservices.comP
ROFESSIONAL
P
ROFILE
Laboratory Director
with the experience and hands-on laboratory expertise essential for contributing
in analytical chemistry, microbiology, in-vitro toxicology, immunology, molecular biology, and
biochemical engineering-related research capacities, and with the knowledge of principles of the Good
Laboratory Practice (GLP). Proven track record in product development, from laboratory to
manufacturer. Energetic, confident leader with a strong drive for efficiency, simplicity, and excellence.
Readily accepts change and new challenges, applying natural abilities in project management, team
building, and verbal / written communications.
►
Expertise in:
analytical HPLC and LCMS analysis… GCMS analysis… ICPMS analysis…
microbiological examinations… cell / tissue culture… DNA / RNA isolation… immunoprecipitation…
northern and western blot… expression vector construction… oligonucleotide primer design… DNA
sequencing… DNA transformation and transfection… PCR and quantitative RT-PCR… in vitro
cytotoxicity and genotoxicity studies under compliance of GLP…SOP writing…
►
Strong technical and theoretical background in:
DNA damage and repair, cancer biology, cytokine
biology, and T-cell immunology, including: in vitro and in vivo transgenic T-cell proliferation,
activation, and differentiation assay… adoptive transfer technique… CTL Assay… apoptosis assay…
flow cytometry analysis
►
Skilled in rodent animal models,
in fungus infection study, T-cell related immune system studies, and
skin fibrosing disease studies, specifically:
… lab animal handling… genotyping… phenotyping…
small animal dissection surgical skills
►
Biochemical engineering experience in:
laboratorial / industrial scale fermentation, from 0.6 liter to
120 ton of fermenter… online analysis of fermentation procedures
►
Proficient in:
online search and analysis of information and databases for research projects
P
ROFESSIONAL
E
XPERIENCE
Spectrix Analytical Services, LLC
2013-present
Senior Microbiologist /Laboratory Director
Quantitate active ingredients and impurities/contaminants of dietary supplements or pharmaceutical
materials using LCMS, GCMS, ICPMS, etc.
Establish biosafety level 2 Microbiology Laboratory for microbiological examinations on customers’
products.
Obtain the laboratory accreditation (ISO/IEC 17025) for Microbiology Laboratory.
MB Research Laboratories, Spinnerstown, PA
2005-2013
Study Director / Research Scientist
Conduct alternative in-vitro toxicity/genotoxicity tests for cosmetics and pharmaceutical industrial
under compliance of GLP.
Lead the project of the in-vitro detection for unscheduled DNA synthesis by using flow cytometric
technology, which is funded by NCI for SBIR.
Write SOP for in vitro toxicology studies.
AOAC OMB Meeting Book
266