Program Book - page 13

13
Biophysical Society 58th Annual Meeting, San Francisco, California
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Sunday, February 16
7:30 am–8:30 am, Room 302
Postdoctoral Breakfast
Supported by the Burroughs Wellcome Fund.
This breakfast presents an opportunity for postdoctoral members of the
Society to meet and discuss the issues they face in their current career
stage. Members of the Early Careers Committee will discuss careers in
industry. They will also be available to answer questions about how the
Committee serves postdocs in the biophysical community and to recruit
new Committee members. Limited to the first 100 attendees.
Speakers:
Andrew Whitley, HORIBA Instruments, Inc.
Avia Rosenhouse-Dantsker, University of Illinois at Chicago
7:30 am–5:00 pm, North Lobby
Registration/Exhibitor Registration
7:30 am–10:00 pm, Room 112
Family Room
8:00 am–8:45 am, Room 123
Exhibitor Presentation
FEI Company
High End Microscope Platform for Multimodal Live Cell Imaging
Ultimately, the secrets of life can only be studied in the living stage -
dynamic processes have to be followed in space and time in living cells to
fully understand their interplay. Successful live cell imaging experiments
require minimizing the phototoxicity while the acquisition speed has
to match the dynamics of the process to be studied. Especially on rare
samples, extraction of the highest possible amount of data from a single
experiment is needed.
The iMIC, our digital fluorescence microscope, has been optimized to
meet the challenges of live cell imaging. It offers fast measurement at
best sensitivity and minimal bleaching. Depending on the sample and
the process to be studied, a variety of specialized microscopy techniques
can be chosen to optimize the result. Fast wide-field imaging, spinning
disc confocal, FRAP and FRET can be combined in one flexible setup
and used on the same sample. Moreover FEIs unprecedented solution for
TIRF imaging makes the iMIC an even more valuable instrument.
TIRF is the way to get superior Z resolution using affordable laser and
camera technology. However, constant need for realignment and inhomo-
geneous excitation have been drawbacks of this technology, especially for
quantitative measurements. Our motorized multi-point TIRF module,
giving full control over penetration depth for different excitation wave-
lengths, automatically adjusted TIRF angle and a simple user interface,
brings the application to a next level. To monitor even fast processes in
living cells utilizing different modalities, switching between TIRF, epi-
fluorescence or FRAP is possible within milliseconds, using our Polytrope
imaging mode switch.
FEI’s proprietary confocal spinning disk design excels with superior resolu-
tion and best alignment of color channels in multi-color 3D image stacks.
Transmission through the disk is enhanced by micro-mirrors, not micro-
lenses. This concept allows us to achieve perfect achromatic correction in
the wavelength range of 405 to 700nm.
Most imaging techniques can also be combined with our two-photon micros-
copy solution. Based on the renowned digital Yanus laser scanner and GaAsP
photomultipliers with large sensitive surface, the two-photon implementation
yields very large fields of view with perfect resolution corner to corner.
Presenters:
Meike Pedersen, Product Marketing Manager, FEI Munich GmbH
Tilman Franke, Product Marketing Manager, FEI Munich GmbH
Gregor Heiss, Product Marketing Engineer, FEI Munich GmbH
8:00 am–5:30 pm, Room 300
Career Center
8:00 am–6:00 pm, Marriott Marquis, Pacific H, I, J
Child Care
8:00 am–6:00 pm, Rotunda, 300 Level
Undergraduate Student Lounge
This special space is reserved for undergraduate meeting attendees looking
for a place to relax or catch up on coursework they may be missing while
at the Annual Meeting. Members of the Education Committee, which
sponsors this lounge, will stop by to answer questions student attendees
may have about career paths and opportunities.
8:00 am–10:00 pm, Hall D
Poster Viewing
8:15 am–10:15 am, Room 134
Symposium
Membrane Transport in Fatty Acid Synthesis
and Obesity
Co-Chairs
Ana Pajor, University of California, San Diego
Da-Neng Wang, New York University School of Medicine
76-Symp 8:15 am
SODIUM-DEPENDENT DICARBOXYLATE AND CITRATE
TRANSPORTERS OF THE SLC13 FAMILY. Ana M. Pajor
77-Symp 8:45 am
STRUCTURE AND MECHANISM OF A BACTERIAL SODIUM-
DEPENDENT DICARBOXYLATE TRANSPORTER. Romina Man-
cusso, Da-Neng Wang
78-Symp 9:15 am
I’M NOT DEAD YET: FLIES AND MICE. Andreas L. Birkenfeld,
Varman T. Samuel, Gerald I. Shulman, Rafael De Cabo, Robert A. Re-
enan, Chen-Tseh Zhu, Stephen Helfand
79-Symp 9:45 am
IN VIVO NMR STUDIES ON THE MECHANISM OF LIPID-
INDUCED INSULIN RESISTANCE IN HUMANS. Gerald I. Shulman
8:15 am–10:15 am, Room 135
Symposium
Force Generation in Cell and Tissue Networks
Co-Chairs
Michael Sheetz, Columbia University
Clare Waterman, NHLBI
80-Symp 8:15 am
MECHANOSENSING BY TROPOMYOSIN-CONTROLLED
MYOSIN CONTRACTIONS. Michael Sheetz