22
Biophysical Society 58
th
Annual Meeting, San Francisco, California
189-S
ymp
4:20
pm
CRYSTAL STRUCTURES OF ACTIVATED G-PROTEIN COUPLED
RECEPTORS.
WilliamWeis
190-S
ymp
4:40
pm
COMBINING CRYSTALLOGRAPHIC AND STRUCTURE-
MODELING APPROACHES IN MACROMOLECULAR
CRYSTALLOGRAPHY.
Thomas C. Terwilliger
, Frank DiMaio,
Randy J. Read, David Baker, Axel T. Brunger, Paul D. Adams,
Pavel V. Afonine, Li-Wei Hung
191-S
ymp
5:00
pm
STRUCTURES OF THE UNIVERSAL TRANSLATOR, THE
RIBOSOME.
Jamie H. D. Cate
192-S
ymp
5:20
pm
XFELS FOR IMAGING MOLECULAR DYNAMICS.
John Spence
193-S
ymp
5:40
pm
THE NEXT 100 YEARS OF CRYSTALLOGRAPHY: HOW THE
HECK SHOULD I KNOW?
Gregory A. Petsko
4:00
pm
–6:00
pm
, R
oom
130/131
Symposium
Liquid Protein Assemblies in Spatial
Organization and Ultrasensitive Signaling in Cells
Co-Chairs
Julie Forman-Kay, Hospital for Sick Children, Canada
Tanja Mittag, St. Jude Children’s Research Hospital
194-S
ymp
4:00
pm
PHASE SEPARATION OF DISORDERED PROTEIN IN THE FOR-
MATION OF MEMBRANE-LESS ORGANELLES. Timothy J. Nott,
Patrick Farber, Evangelia Petsalakis, Dylan Jervis, Andrew J. Baldwin,
Julie D. Forman-Kay
195-S
ymp
4:30
pm
THE LIQUID STATE OF (ELASTOMERIC) PROTEINS.
Régis Pomès
196-S
ymp
5:00
pm
DECODING MOLECULAR PLASTICITY UNDERLYING
NUCLEOCYTOPLASMIC TRANSPORT: FROM SINGLE
MOLECULES TO LARGE ASSEMBLIES.
Edward A. Lemke
197-S
ymp
5:30
pm
PHASE SEPARATION OF MULTI-VALENT SIGNALING
PROTEINS.
Michael K. Rosen
4:00
pm
–6:00
pm
, R
oom
132/133
Platform
Voltage-gated Na Channels
Co-Chairs
Bonnie Wallace, Birkbeck College, United Kingdom
Jonathan Silva, Washington University in St. Louis
198-P
lat
4:00
pm
STRUCTURE/FUNCTION INSIGHTS INTO EUKARYOTIC
CHANNEL BLOCKER BINDING SITES IN A PROKARYOTIC
SODIUM CHANNEL.
Claire Bagnéris
, Claire E. Naylor,
Paul G. DeCaen, David E. Clapham, David Pryde, B. A. Wallace
199-P
lat
4:15
pm
INTRACELLULAR CALCIUM ATTENUATES PERSISTENT
CURRENT CONDUCTED BY MUTANT HUMAN CARDIAC
SODIUM CHANNELS IN LONG-QT SYNDROME.
Franck Potet
,
Thomas M. Beckermann, Jennifer D. Kunic, Alfred L. George
200-P
lat
4:30
pm
SINGLE-PARTICLETRACKING PALMOF NAV1.6 INHIPPOCAMPAL
NEURONS DEMONSTRATES UNIQUE SUBCELLULAR DIFFUSION
LANDSCAPES.
Elizabeth J. Akin
, Kristen Brown, Sanaz Sadegh,
Aubrey V. Weigel, Jean-Baptiste Masson, Diego Krapf, Michael M. Tamkun
201-P
lat
4:45
pm
β
4 MODULATES NA
V
1.2 TOXIN PHARMACOLOGY.
John M. Gilchrist
, Samir Das, Filip Van Petegem, Frank Bosmans
202-P
lat
5:00
pm
DISTINCT VOLTAGE SENSOR GATING OF CARDIAC NA
V
CHANNELS.
Zoltan Varga
, Angela R. Schubert, Alexandra B. Asaro,
Jianmin Cui, Mark A. Zaydman, Colin G. Nichols, Jonathan R. Silva
203-P
lat
5:15
pm
CRYSTAL STRUCTURE OF THE NAV
β
4 EXTRACELLULAR
DOMAIN.
Samir Das
, John Gilchrist, Frank Bosmans, Filip Van Petegem
204-P
lat
5:30
pm
MOLECULAR DYNAMICS STUDIES OF ION CONDUCTION IN
A PROKARYOTIC CHANNEL.
Karen M. Callahan
, Benoit Roux
205-P
lat
5:45
pm
PHOSPHOPROTEOMIC IDENTIFICATION OF CAMKII- AND
HEART FAILURE-DEPENDENT PHOSPHORYLATION SITES ON
THE NATIVE CARDIAC NAV1.5 CHANNEL PROTEIN.
Fabien Coyan, Sophie Burel, Cheryl F. Lichti, Joan H. Brown,
Flavien Charpentier, Jeanne M. Nerbonne, Reid R. Townsend,
Lars M. Maier,
Céline Marionneau
4:00
pm
–6:00
pm
, R
oom
303
Platform
Molecular Dynamics I
Co-Chairs
Cameron Mura, University of Virginia
Karissa Sanbonmatsu, Los Alamos National Laboratory
206-P
lat
4:00
pm
CONFORMATIONAL DYNAMICS DURING GPCR - G PROTEIN
COUPLING.
Alexander S. Rose
, Matthias Elgeti, Patrick Scheerer,
Ulrich Zacchariae, Martin Heck, Franz J. Bartl, Helmut Grubmüller,
Klaus P. Hofmann, Peter W. Hildebrand
207-P
lat
4:15
pm
MODELING AND INHIBITOR DESIGN OF CA(
2+
)-INDEPENDENT
PHOSPHOLIPASE A2.
Denis Bucher
, Varnavas D. Mouchlis,
Edward A. Dennis, J Andrew McCammon
208-P
lat
4:30
pm
MEMBRANE DEPENDENCE OF THE MECHANOSENSITIVE
CHANNEL OF LARGE CONDUCTANCE.
Helgi I. Ingólfsson
,
Clement Arnarez, Neeraj Kumar, Martin Walko, Herman J. C. Berendsen,
Armağan Koçer, Siewert J. Marrink
209-P
lat
4:45
pm
UNDERSTANDING THE SPECIAL PROPERTIES OF [NIFESE]
HYDROGENASES THROUGH THE USE OF COMPUTATIONAL
METHODOLOGIES.
Carla SA Baltazar
, Victor H. Teixeira,
Cláudio M. Soares
210-P
lat
5:00
pm
STRUCTURAL INSIGHTS ON THE STATHERIN N-TERMINAL
BINDING DOMAIN IN THE ADSORBED STATE.
Michael Deighan
, Tobias Weidner, Jim Pfaendtner
