16
Biophysical Society 58
th
Annual Meeting, San Francisco, California
120-P
lat
9:15
am
SINGLE-MOLECULE TRACKING OF SMOOTHENED IN THE
PRIMARY CILIUM.
Lucien E. Weiss
, Ljiljana Milenkovic, Steffen J. Sahl,
Theodore L. Roth, Matthew P. Scott, W E. Moerner
121-P
lat
9:30
am
DIFFERENTIAL CLUSTERING OF SRC FAMILY KINASE ON
LIPID BILAYERS REGULATES A NET PHOSPHORYLATION
ACTIVITY IN A RECEPTOR-KINASE-PHOSPHATASE NETWORK.
Gabriela Furlan, Li Huang, Takashi Minowa, Nobutaka Hanagata,
Chiho Kataoka,
Yoshihisa Kaizuka
122-P
lat
9:45
am
OPTICAL PROBING OF METABOTROPIC GLUTAMATE
RECEPTOR ASSEMBLY AND COOPERATIVITY.
Josh Levitz
,
Shashank Bharill, Reza Vafabakhsh, Ehud Y. Isacoff
123-P
lat
10:00
am
THE STRUCTURE AND OLIGOMERICITY OF THE
TRANSMEMBRANE DOMAIN OF CYTOKINE RECEPTORS IS
MODULATED BY THE PROTEIN/LIPID RATIO.
Katrine Bugge
,
Kresten Lindorff-Larsen, Michael J. Waters, Vincent Goffin,
Birthe B. Kragelund
8:15
am
–10:15
am
, R
oom
306
Platform
Protein-Nucleic Acid Interactions I
Co-Chairs
Marco Capitanio, University of Florence, Italy
Timothy Blosser, Delft University of Technology, The Netherlands
124-P
lat
8:15
am
PROTEIN DNA INTERACTION MEASURED WITH ULTRA FAST
FORCE CLAMP OPTICAL TWEEZERS. Carina Monico,
Alessia Tempestini, Francesco Vanzi, Francesco Pavone,
Marco Capitanio
125-P
lat
8:30
am
MECHANICAL CHARACTERIZATION OF A FAST DNA MOTOR:
SPOIIIE.
Ninning Liu
, Gheorghe Chistol, Carlos Bustamante
126-P
lat
8:45
am
international
travel
awardee
STUDYING PROTEIN-DNA DYNAMICS AND PROTEIN
UNFOLDING USING A FORCE-FREE SINGLE-MOLECULE
TECHNIQUE.
Guy Nir
, Moshe Lindner, Yuval Garini
127-P
lat
9:00
am
MULTIPLE LAC-MEDIATED LOOPS REVEALED BY BAYESIAN
STATISTICS ANDTETHERED PARTICLE MOTION.
Martin Lindén
,
Stephanie Johnson, Jan-Willem van de Meent, Rob Phillips, Chris Wiggins
128-P
lat
9:15
am
SUBSTRATE RECOGNITION AND SPECIFICITY OF DOUBLE-
STRANDED RNA BINDING PROTEINS.
Lela Vukovic
,
Hye Ran Koh, Sua Myong, Klaus Schulten
129-P
lat
9:30
am
MOLECULAR MECHANISM OF INHIBITION OF THE PKR-RNA
INTERACTION BY THE INFLUENZA A VIRUS NS1 PROTEIN–
A THREE COLOUR BASED FLIM-FRET APPROACH IN LIVING
CELLS.
Fabian Jolmes
, Sieben Christian, Thorsten Wolff,
Andreas Herrmann
130-P
lat
9:45
am
ELUCIDATING RESTRICTION ENDONUCLEASES REACTION
MECHANISMS
VIA
DWELL-TIME DISTRIBUTION ANALYSIS.
Candice M. Etson
, Petar Todorov, David R. Walt
131-P
lat
10:00
am
DEFENSE AGAINST VIRAL ATTACK: SINGLE-MOLECULE VIEW
ON A BACTERIAL ADAPTIVE IMMUNE SYSTEM.
Timothy Blosser
,
Edze Westra, Luuk Loeff, Cees Dekker, Stan Brouns, Chirlmin Joo
9:00
am
–10:00
am
, R
oom
300
Career Center Workshop Beyond the Bench:
Preparing for Your Career Transition
in the Life Sciences
There are numerous alternative career options for the seasoned bench scientist
who may have decided to take his/her talents and apply them in a new direc-
tion. This transition can be accomplished without having to matriculate in
another graduate program, and this session explores the how’s and why’s of
making such a transition. Be prepared to talk about the role you are thinking
about moving into, why you may have chosen this alternative path, and what
successes you may have had thus far.
9:00
am
–10:30
am
, R
oom
122
CPOW Committee Meeting
9:00
am
–10:30
am
, R
oom
123
Exhibitor Presentation
Forte Bio, A Division of Pall Life Sciences
Developing Assays for Kinetic Characterization on the BLItz System
The BLItz system is a simple-to-use, affordable label-free assay system
capable of delivering rich insight into real-time binding interactions of
antibodies and proteins. This workshop will present several case studies
of how the BLItz system is being used to validate biophysical models.
As part of the workshop, learn tips and tricks for developing a kinetics
assay on the BLItz system and take the opportunity to perform a
hands-on demo of the system.
Presenter:
Renee Tobias, Applications Scientist, Pall ForteBio
10:00
am
–5:00
pm
, H
all
D
Biomolecular Discovery Dome
Visit this 3-D portable Dome, sponsored by the Public Affairs Committee, to
see how difficult biophysical topics can be made accessible to the public.
Short videos that communicate the excitement of looking at macromo-
lecular complexes and understanding the molecular basis for life are being
shown throughout the week.
10:00
am
–5:00
pm
, H
all
D
Exhibits
10:15
am
–11:00
am
, H
all
D
Coffee Break
10:30
am
–11:30
am
, R
oom
300
Career Center Workshop Career Catalyst:
Understand Who You Are to Get What You Want
Confucius said: “Learning without thought is labor lost; thought without
learning is perilous.” Consider investing some time in this updated self-
reflection workshop to learn, think and talk about whom you are and what
you want. Truly understanding yourself—your likes/dislikes, your passions,
preferences, and personality quirks—can lead not only to career success but
to a happy and fulfilling life. This workshop will provide tools and tech-
niques to help you translate self-reflection into meaningful career choices.
