18
Biophysical Society 58
th
Annual Meeting, San Francisco, California
147-P
lat
11:30
am
STRUCTURAL BASIS OF CONFORMATIONAL TRANSITIONS
INVOLVED IN PSEUDOPILUS ASSEMBLY AND STABILITY.
Michael Nilges
, Mangayarkarasi Nivaskumar, Guillaume Bouvier,
Manuel Campos, Edward H. Egelman, Xiong Yu, Olivera Francetic
148-P
lat
11:45
am
A SINGLE INTER-DOMAIN SALT BRIDGE WITHIN THE
HUMAN ARGONAUTE 2 PROTEIN CRUCIALLY AFFECTS
PROTEIN FOLDING AND CONSEQUENTLY ENZYMATIC
ACTIVITY.
Munishikha Kalia
, Sarah Willkomm,
Jens Christian Claussen, Alexandre M.J.J. Bonvin, Tobias Restle
149-P
lat
12:00
pm
MECHANISMS OF SUBSTRATE DEGRADATION BY ENERGY-
DEPENDENT PROTEASES.
Andreas Martin
, Mary Matyskiela,
Kristofor Nyquist, Gabriel Lander, Robyn Beckwith, Eric Estrin, EvanWorden
150-P
lat
12:15
pm
STRUCTURE, DYNAMICS, EVOLUTION AND FUNCTION
OF A MAJOR SCAFFOLD COMPONENT IN THE NUCLEAR
PORE COMPLEX.
Seung Joong Kim
, Parthasarathy Sampathkumar,
Paula Upla, William Rice, Jeremy Phillips, Benjamin Timney,
Javier Fernandez-Martinez, Andrej Sali, Michael Rout,
Steven Almo
151-P
lat
12:30
pm
STRUCTURAL GYMNASTICS BY PROTEINS MAKE THE CLOCK
MECHANISM GO ROUND AND ROUND. Yong-Gang Chang,
Roger Tseng, William K. Myers, Jonathan Kerby, David Britt,
Andy LiWang
10:45
am
–12:45
pm
, R
oom
303
Platform
Bioenergetic Processes in Bacteria,
Chloroplasts, and Mitochondria
Co-Chairs
Gabriela Schlau-Cohen, Stanford University
Wang Wang, University of Washington
152-P
lat
10:45
am
SINGLE-MOLECULE LIVE-CELL IMAGING OF BACTERIAL
RESPIRATORY COMPLEXES INDICATES OXPHOS
DELOCALIZATION.
Mark Leake
153-P
lat
11:00
am
CARDIOLIPINS AT THE INTERFACE OF SUPERCOMPLEXES IN
THE RESPIRATORY CHAIN.
Clement Arnarez
, Siewert-Jan Marrink,
Xavier Periole
154-P
lat
11:15
am
ELUCIDATION OF THE PHOTODYNAMICS OF SINGLE
PHOTOSYNTHETIC LH2 COMPLEXES IN SOLUTION.
Gabriela S. Schlau-Cohen
, Quan Wang, June Southall,
Richard J. Cogdell, W.E. Moerner
155-P
lat
11:30
am
MECHANISM OF WATER SPLITTING BY PHOTOSYSTEM II.
Yulia Pushkar
, Katherine Davis, Lifen Yan
156-P
lat
11:45
am
STRUCTURAL COUPLING OF THE EF HAND AND
C-TERMINAL GTPASE DOMAINS IN THE
MITOCHONDRIAL PROTEIN MIRO.
Julian Klosowiak
,
Pamela Focia, Srinivas Chakravarthy, Eric Landahl, Douglas Freymann,
Sarah Rice
157-P
lat
12:00
pm
INTERACTION OF THE BAK HOMODIMER WITH THE
MEMBRANE. Sreevidya Aluvila, Tirtha Mandal,
Kyoung Joon Oh
158-P
lat
12:15
pm
FISSION PROMOTES RESPIRATION AND ROS PRODUCTION
IN INDIVIDUAL MITOCHONDRIA.
Huiliang Zhang
,
Shey-Shing Sheu, Wang Wang
159-P
lat
12:30
pm
THE CORRELATION BETWEEN UCP EXPRESSION UND
CELLULAR METABOLISM.
Anne Rupprecht
, Dana Sittner,
Alina Smorodchenko, Karolina E. Hilse, Rudolf Moldzio,
Andrea E. M. Seiler, Anja U. Bräuer, Elena E. Pohl
10:45
am
–12:45
pm
, R
oom
304
Platform
Ligand-gated Channels I
Co-Chairs
Andrew Plested, Leibniz-Institut für Molekulare Pharmakologie (FMP), Germany
Ehud Isacoff, University of California, Berkeley
160-P
lat
10:45
am
ENERGETIC COUPLING OF THE LIGAND BINDING DOMAIN
TO PORE OPENING IN NMDA RECEPTORS.
Rashek Kazi
,
Jian Dai, Melissa Daniel, Huan-Xiang Zhou, Lonnie P. Wollmuth
161-P
lat
11:00
am
REGULATORY IONS BOUND AT THE IGLUR LIGAND
BINDING DOMAIN DIMER INTERFACE -
A SHARED PROPERTY OF GLUK2 AND AVGLUR1?
Maria Musgaard
, Jack Barber, M. Khadeesh bin Imtiaz, Philip C. Biggin
162-P
lat
11:15
am
NMDA AND AMPA RECEPTOR LIGAND-BINDING DOMAINS
EXHIBIT SUBTYPE-SPECIFIC CONFORMATIONAL PROPENSITIES.
John Belcher, Yongneng Yao, Anthony Berger, Mark L. Mayer,
Albert Y. Lau
163-P
lat
11:30
am
PROBING THE CHANNEL GATING OF A GLUTAMATE
RECEPTOR WITH A PHOTOACTIVE UNNATURAL AMINO
ACID.
Viktoria Klippenstein
, Andrew J. Plested
164-P
lat
11:45
am
ACTIVATION OF LIGAND BINDING DOMAINS OF AN
AMPA-TYPE GLUTAMATE RECEPTOR.
Jelena Baranovic
,
Miriam Chebli, Hector P. Salazar, Katja Faelber, Valentina Ghisi,
Albert Y. Lau, Oliver Daumke, Andrew J R Plested
165-P
lat
12:00
pm
PROBING THE GATING OF IONOTROPIC GLUTAMATE
RECEPTORS WITH TETHERED PHOTOSWITCHABLE LIGANDS.
Andreas Reiner
, Ehud Y. Isacoff
166-P
lat
12:15
pm
OCCUPANCY OF A SINGLE BINDING SITE IS SUFFICIENT
FOR AMPAR ACTIVATION.
Indrani Bhattacharyya
, Rikard Blunck
167-P
lat
12:30
pm
IMAGED BY CRYO-EM, ACTIVATED AND DESENSITIZED
GLUA2 GLUTAMATE RECEPTORS SHOW EXTREME FLEXIBILITY.
Hideki Shigematsu
, Youshan Yang, Yangyang Yan, Katharina Duerr,
Eric Gouaux, Fred J. Sigworth
