15
Biophysical Society 58
th
Annual Meeting, San Francisco, California
S
A
T
U
R
D
A
Y
F
R
I
D
A
Y
U
N
D
A
Y
8:15
am
–10:15
am
, R
oom
303
Platform
Protein-Lipid Interactions I
Co-Chairs
Scott Feller, Wabash College
Ka Yee Lee, University of Chicago
100-P
lat
8:15
am
REPLICA EXCHANGE UMBRELLA SAMPLING SIMULATIONS
PROVIDE INSIGHT INTO THE ROLE OF DOCOSAHEXAENOIC
ACID IN MODULATING THE STABILITY OF TRANSMEMBRANE
PROTEINS. Ryan Snyder, Bo Wang, Matthew Roark,
Scott E. Feller
101-P
lat
8:30
am
PROTON-COUPLED WATER AND HYDROGEN-BOND
DYNAMICS IN CHANNELRHODOPSIN. Christopher Mielack,
Coral del Val, Maria Luiza Bondar,
Ana Nicoleta Bondar
102-P
lat
8:45
am
APPLICATION OF THE VIRTUAL SITE TECHNIQUE TO LIPIDS
IN GROMACS, HYDROGENS DEGREES OF FREEDOM
REMOVAL AND PERFORMANCE INCREASE.
Bastien Loubet
,
Wojciech Kopec, Himanshu Khandelia
103-P
lat
9:00
am
MOLECULAR DETAILS OF
α
-SYNUCLEIN MEMBRANE
ASSOCIATION REVEALED BY NEUTRON REFLECTOMETRY.
Jennifer C. Lee
, Zhiping Jiang, Sara Hess, Ryan P. McGlinchey,
Thai Leong Yap, Frank Heinrich
104-P
lat
9:15
am
UNDERSTANDING PROTEIN-MEMBRANE INTERACTIONS
VIA FREE ENERGY CALCULATIONS.
Joakim P. M. Jämbeck
,
Alexander P. Lyubartsev
105-P
lat
9:30
am
A MOLECULAR MECHANISM FOR DIFFERENTIAL
RECOGNITION OF MEMBRANE PHOSPHATIDYLSERINE
BY THE IMMUNE REGULATORY RECEPTOR TIM4.
Gregory T. Tietjen, Zhiliang Gong, Chiu-Hao Chen, Ernesto Vargas,
James E. Crooks, Kathleen D. Cao, Charles T.R. Heffern,
J. Michael Henderson, Benoit Roux, Mati Meron, Binhua Lin,
Mark Schlossman, Theordore L. Steck, Erin J. Adams,
Ka Yee C. Lee
106-P
lat
9:45
am
THE POINT OF NO RETURN; 3D STRUCTURE OF BAX-MEDIATED
PORES IN MEMBRANE BILAYERS.
Dorit Hanein
, Xiao-Ping Xu,
Dayong Zhai, Eldar Kim, Mark Swift, John C. Reed, Niels Volkmann
107-P
lat
10:00
am
VOLTAGE- AND CALCIUM-DEPENDENT TOXIN
TRANSLOCATION ACROSS A TETHERED LIPID BILAYER.
Joel Chopineau
, Remi Veneziano, Claire Rossi, Jean-Marie Devoisselle,
Alexandre Chenal, Daniel Ladant
8:15
am
–10:15
am
, R
oom
304
Platform
Biosensors
Co-Chairs
Leon Harrington, University of Oxford, United Kingdom
Mikhail Shapiro, California Institute of Technology
108-P
lat
8:15
am
ELECTROSTATICALLY ENHANCED ASSOCIATION OF A PIM
KINASE SUBSTRATE REVEALED BY STOCHASTIC DETECTION.
Leon Harrington
, Stephen Cheley, Leila T. Alexander, Stefan Knapp,
Hagan Bayley
109-P
lat
8:30
am
PROBING DNA METHYLATION IN BREAST CANCER CELL
LINES USING SOLID-STATE NANOPORES.
Azadeh Bahrami
,
Eric W. Lam, Tim Albrecht
110-P
lat
8:45
am
LABEL-FREE DETECTION OF THE P53-DNA COMPLEX.
Philippa Nuttall
, Eric Lam, Tim Albrecht
111-P
lat
9:00
am
THERMODYNAMIC CHARACTERIZATION OF PROTEINS
WITH ELECTRICALLY ACTUATED DNA NANOLEVERS.
ThomasWelte
, Ralf Strasser, Frank Fischer, Wolfgang Kaiser, Ulrich Rant
112-P
lat
9:15
am
EVALUATING INTRACELLULAR CROWDED WITH A
GLYCINE-INSERTED MUTANT FLUORESCENT PROTEIN.
Takamitsu J. Morikawa
, Hiroaki Machiyama, Kazuko Okamoto,
Keiko Yoshizawa, Hideaki Fujita, Taro Ichimura, Katsumi Imada,
Takaharu Nagai, Toshio Yanagida, Tomonobu M. Watanabe
113-P
lat
9:30
am
NIR FLUORESCENT PROTEINS WITH SYNTHETIC
CHROMOPHORES FOR DEEP TISSUE IMAGING.
Ming Zhang
114-P
lat
9:45
am
GENETICALLY ENCODED GAS NANOSTRUCTURES AS
BIOPHYICALLY TUNABLE MOLECULAR REPORTERS FOR
MRI AND ULTRASOUND.
Mikhail G. Shapiro
115-P
lat
10:00
am
LABEL-FREE OPTICAL DETECTION AND SUPER-RESOLUTION
MICROSCOPY OF SINGLE PROTEINS.
Vahid Sandoghdar
,
Marek Piliarik
8:15
am
–10:15
am
, R
oom
305
Platform
Membrane Receptors and Signal
Transduction I
Co-Chairs
Monica Mazzolini, SISSA, Italy
Geoffrey O’Donoghue, University of California, Berkeley
116-P
lat
8:15
am
DIRECT, SINGLE MOLECULE, CELL-BY-CELL OBSERVATION
OF MOLECULAR KINETICS AND THERMODYNAMICS IN
EARLY LYMPHOCYTE SIGNALING.
Geoffrey P. O’Donoghue
,
Rafal Pielak, Jenny J. Lin, Jay T. Groves
117-P
lat
8:30
am
RESTRICTED SPOTS OF LIGHT REVEAL AN EFFICACY
GRADIENT OF THE PHOTOTRANSDUCTION CASCADE
ALONG THE ROD OUTER SEGMENT.
Monica Mazzolini
,
Laura Andolfi, Giuseppe Facchetti, Marco Lazzarino,
Remo Proietti Zaccaria, Salvatore Tuccio, Johannes Treu, Claudio Altafini,
Enzo Di Fabrizio, Gert Rapp, Vincent Torre
118-P
lat
8:45
am
USING MAGNETIC PROBES TO STUDY RECEPTOR
CLUSTERING IN LIVE CELLS.
Burcu Celikkol
, Alessandra Cambi,
Carl G. Figdor, Vinod Subramaniam, Johannes S. Kanger
119-P
lat
9:00
am
TOWARD SINGLE-MOLECULE IMAGING OF ELECTROPORATED
BACTERIAL FLAGELLAR MOTOR PROTEINS IN
MOTILE E. COLI.
Diana Di Paolo
