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21

September 27–30, 2015

|

 Westin Bonaventure Hotel

|

 Los Angeles, California

SCIENTIFIC SESSIONS – WEDNESDAY

Roundtable: Progress and Remaining

Challenges in the Control of Marine Biotoxins

Increasing knowledge in various aspects of the control of

marine biotoxins, particularly the transition from mouse

bioassays to chemical methods, prompts more extensive

discussions of these important developments as well as

challenges that still remain unresolved. In contrast to mouse

bioassays, modern chemical methods have the ability for

identification, quantitation or even confirmation of the

presence of the various toxins, and overall performance

continues to advance including higher instrument sensitiv-

ity. These method improvements, in addition to improved

sample pretreatment protocols are clearly important,

however there are critical issues to address in improved

toxicological evaluation and risk management, and even

new legislation. Although concerted efforts have been

made in these areas in the last few years, some unresolved

issues need to be addressed. This roundtable will face

these issues, in particular analytical aspects of improved

methodologies, the need for method harmonization, and for

improved toxicological evaluations thru oral feeding studies.

Furthermore risk management issues, legislation, and also

the impact of these issues on the bivalve fishery industry

will be discussed.

CO-CHAIR:

Ana Gago-Martinez,

University of Vigo and EURLMB

CO-CHAIR:

James Hungerford,

U.S. FDA

Ana Gago-Martinez,

University of Vigo and EURLMB

James Hungerford,

U.S. FDA

Pearse McCarron,

National Research Council Canada

Carlos Ruiz,

ANFACO, CECOPESCA

Joerg Stroka,

European Commission - JRC – IRMM

AOAC INTERNATIONAL Stakeholder Panels

Update: ISPAM, SPADA, SPDS, SPIFAN, and

SPSFAM

AOAC INTERNATIONAL Stakeholder Panels are creat-

ing voluntary based consensus based standards meeting

industry needs. Attend this session to get an update on

each of the stakeholder panels: International Stakeholder

Panel on Alternative Methodology (ISPAM), Stakeholder

Panel on Agent Detection Assays (SPADA), Stakeholder

Panel on Dietary Supplements (SPDS), Stakeholder Panel

on Infant Formula and Adult Nutritionals (SPFIAN), and the

Stakeholder Panel on Strategic Food Analytical Methods

(SPSFAM).

CHAIR:

Jim Bradford,

AOAC INTERNATIONAL

3:00 pm – 4:30 pm

Analytical Challenges and Reporting Frame-

work of Results in Perspective of Sound

Method Performance Requirements

Analytical Methods progressed over time with the need to

either obtaining rapid results at early stage of production

and/or the need to check commodities for a larger array of

substances while recognizing scientific progress address-

ing these needs. As a result classical single analyte/matrix

tend to be displaced with those of a wider scope that serve

more than only one purpose such as compliance checking

against a limit. Additional purposes can be the use for expo-

sure assessments, which require extended working ranges

or multianalyte methods allowing to reduce the analytical

effort. Therefore “swiss army knife” like methods are aimed

at, requiring often new aspects of validation. This session

aims at bringing some light in the challenges analytical

chemists face meeting the needs of scientific progress,

performance demands as well as applicability demands.

CO-CHAIR:

Joerg Stroka,

European Commission - JRC - IRMM

CO-CHAIR:

Susie Y. Dai,

Office of the Texas State Chemist

Paul Zomer,

RIKILT - Institute Of Food Safety

Analyte Identification Criteria for Mass Spec Based

Analytical Methods

Ana Gago-Martinez,

University of Vigo and EURLMB

Analytical Challenges in the Transition from the Mouse

Bio Assay (MBA) to Chemistry for the Analysis of Marine

Biotoxins

Joerg Stroka,

European Commission - JRC - IRMM

A Novel Validation Concept Meeting the Need to Test

against a Single Level