1014 / 1578
/
• Median OS of 9 – 11 months in metastatic
pancreatic cancer with CT alone
Pancreatic cancer – CT only
FOLFIRINOX
Median 11 months
Conroy NEJM 2011
Nab-Paclitaxel
Von Hoff NEJM 2013
Median 8.5 months
ESTRO SBRT 2017 - Matthias Guckenberger
5
/
Ø
Rapid progression of 1/3 of the patients
Pancreatic cancer – LAP 007
Locally advanced pancreatic cancer
4 x Gem
4 x Gem& erlotinib
N=449
Progression free
CT only
N=269
54Gy Cap
ESTRO SBRT 2017 - Matthias Guckenberger
6