1020 / 1578
/
Median OS:
Ø
Borderline resectable PC:
16.4 months
Ø
Locally advanced PC:
15 months
Chuong IJROBP 2013
SBRT to achieve resectability
ESTRO SBRT 2017 - Matthias Guckenberger
17
/
Ø
Fractionated SBRT with lower SFD well tolerated
• Phase 2 multi-institutional study
• 49 pat. with locally advanced PC
o
3 x Gem (1000mg/m2)
o
1 week break
o
SBRT with 5 x 6.6Gy
• Median FU 14 months
SBRT for locally advanced pancreatic cancer
Acute GI Tox G >=2
Late GI Tox G >=2
2%
11%
ESTRO SBRT 2017 - Matthias Guckenberger
18