1021 / 1578
/
Ø
Reasonable OS, despite not being overwhelming
Ø
OS the only relevant endpoint?
Herman Cancer 2015
Median 13.9 months
SBRT for locally advanced pancreatic cancer
ESTRO SBRT 2017 - Matthias Guckenberger
19
/
Ø
Addition of SBRT to CT improved OS compared
CT alone or CT & EBRT
De Geus Cancer 2017
SBRT for locally advanced pancreatic cancer
ESTRO SBRT 2017 - Matthias Guckenberger
20
Analysis of National Cancer Data Base 2004 – 2012:
Ø
unresected nonmetastatic pancreatic adenocarcinoma receiving
chemotherapy
Ø
CT alone or combined with EBRT, IMRT, SBRT
Ø
Propensity Score matching:
age, sex, race, comorbidity, insurance,
type of treatment center, tumor location, and clinical stage
CT
CT & EBRT CT & IMRT CT & SBRT
Median OS 10.2 mo 11.6 mo 12.2 mo 13.9 mo