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SBRT for locally advanced pancreatic cancer
More SBRT dose results in …
• Slightly better local control
• Substantially incerased toxicity
• Worse overall survival
Local control
> G2 toxicity
Overall survival
Systematic literature review: 20 trials / 721 patients
Brunner Radiother Oncol 2015
ESTRO SBRT 2017 - Matthias Guckenberger
13
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ESTRO SBRT 2017 - Matthias Guckenberger
14