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Ø

RCHT well tolerated

Ø

No improvement of OS, median 15 – 16.5 mo

Ø

Boarderline improvement of PFS

Pancreatic cancer – LAP 007

Hammel YAMA 2016

Overall survival

PF survival

ESTRO SBRT 2017 - Matthias Guckenberger

7

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Published illustration

of pancreatic SBRT:

No (obvious) safety margin:

• Imaging for extension of diease?

• Microscopic disease?

• Residual uncertainties?

Despite small (zero) safety margin:

• Full dose to adjacant duodenal

wall

• Relevant doses to intestine

Pancreatic cancer

ESTRO SBRT 2017 - Matthias Guckenberger

8