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INFORMS Philadelphia – 2015

241

MD29

29-Room 406, Marriott

Joint Session Analytics/CPMS: 2015 Innovative

Applications in Analytics Award Winner Reprise

Sponsor: Analytics

Sponsored Session

Chair: Pooja Dewan, BNSF Railway, Fort Worth, TX, 76092,

United States of America,

Pooja.Dewan@bnsf.com

1 - Intelligent Surgical Scheduling System

Kalyan Pasupathy, Associate Professor, Mayo Clinic, 200 First

Street SW, HA 2-43, Rochester, MN, 55905, United States of

America,

Pasupathy.Kalyan@mayo.edu,

Narges Hosseini, Jeanne

Huddleston, Paul Huddleston, Yariv Marmor, Thomas Rohleder

Orthopedic Surgery was facing highly fluctuating utilization of their operating

rooms due to inaccurate estimation and scheduling of procedures. The existing

scheduling optimization problems in literature were insufficient with just a single

“optimal” solution. The team conducted descriptive research of clinical and

operational factors, developed predictive models for surgical durations, and a

prescriptive scheduling algorithm. Implementation results exhibit improvement in

key metrics.

MD30

30-Room 407, Marriott

Practice Presentations by INFORMS Roundtable

Companies III

Sponsor: INFORMS Practice

Sponsored Session

Chair: Stefan Karisch, Digital Aviation Optimization & Value Strategy,

Boeing Commercial Aviation Services, 55 Inverness Drive East,

Englewood, CO, 80112, United States of America,

stefan.karisch@jeppesen.com

1 - Xpress-mosel: New Modeling Features for Distributed and

Cloud Computing

Susanne Heipcke, FICO Xpress Optimization, FICO House,

Starley Way, Birmingham, B37 7GN, United Kingdom,

susanneheipcke@fico.com

A major concern when deploying optimization models in distributed computing

environments are questions related to security for the transmission and storing of

data, and the protection of the model itself - we show examples how these are

adressed by the new Mosel module mmssl. We further discuss the new concept of

model annotations, metadata that can be used to configure optimization

applications, and touch on new interfaces (HTTP, XML, JSON, Hadoop, R).

2 - Solving the Airline Pilot Manpower Planning Problem.

Per Sjügren, Jeppesen systems AB, Odinsgatan 9, Gothenburg,

41311, Sweden,

per.sjogren@jeppesen.com

The pilot manpower planning problem consists of the long term planning of

recruitment and promotion to meet the forecasted crew need. Complicating

factors are strict seniority promotion rules and limited training resources. We

further consider movable activities such as vacation and overtime distribution as

well as required recurrent training. We will present a high level description of the

mixed integer model, the heuristic solution process and successful applications.

3 - Prescriptive Analytics on the Cloud with Python

Vincent Beraudier, Architect And Program Manager, IBM ILOG

CPLEX, Porte Neuve, Bat A, 4 Av Alphonse Morel, Grasse, Al,

06130, France,

vincent.beraudier@fr.ibm.com

,

Philippe Couronne

Python’s scipy provides tools for large-scale predictive/ prescriptive analysis for

manipulating, cleaning, and crunching data, and publication-quality graphics. The

use of these web based tools with both state-of-the art OR solvers and cloud

computing will allow new users to enter the world of OR. Users with few

development skills can leverage state-of-the-art solvers to develop, tune and

publish their results without installing software. Come and discover those

scientific python pillars.

4 - A Mixed Interger Programming Model for Optimizing Wheel

Tru Operations for a Locomotive

Rajeev Namboothiri, GE Global Research,

John F Welch Technology Centre, Bangalore, India,

Rajeev.Namboothiri@ge.com,

Srinivas Bollapragada,

Reejo Mathew, Mark Smith

FRA regulations mandate tolerance limits on locomotive wheel measurements for

safe locomotive operations. The wheel tru machine operator needs to decide the

amount of material to be trued from each wheel, and the wheels that need to be

replaced with inventory wheels, in order to comply with FRA regulations. In this

talk, we will present a novel MIP formulation for automating this complex

decision, which minimizes the total cost of the wheel tru operation, thereby

enhancing locomotive wheel life.

MD32

32-Room 409, Marriott

Big Biological Data: Computational and

Analytical Challenges

Cluster: Big Data Analytics in Computational Biology/Medicine

Invited Session

Chair: Jian Peng, Assistant Professor, University of Illinois, 2118 Siebel

Center, 201 N Goodwin Ave, Urbana, IL, 61801, United States of

America,

jianpeng@illinois.edu

1 - Reconstruction of Species Histories using Genomic Data

Siavash Mirarab, UCSD, Jacobs Hall, EBU1, 2nd Floor, University

of California, San Diego, San Diego, CA, 92093, United States of

America,

smirarab@gmail.com

, Shamsuzzoha Bayzid,

Bastien Boussau, Tandy Warnow

Reconstructing phylogenies, trees that show evolutionary histories of species, can

be now attempted using genomic data. Building these species trees is complicated

by potential differences between evolutionary histories across the genome. In this

talk, we introduce two new methods used to infer whole-genome phylogenies of

48 birds and 103 plants. These new algorithms can analyze datasets with

thousands of genes and species with high accuracy, and can account for weak

signal across the genome.

2 - Entropy-Scaling Search of Massive Biological Data Sets

Noah Daniels, MIT, 32 Vassar St., 32G-572, Cambridge, MA,

02139, United States of America,

ndaniels@csail.mit.edu

Recently, we have seen an exponential increase in biological data, outpacing

advances in computing power. Extracting new science from these massive

datasets requires algorithms that scale sublinearly in the size of the datasets. We

present a novel entropy-scaling data structure for similarity search. Applying this

data structure provides massive acceleration of several standard tools in three

biological domains: genomics, high-throughput drug screening, and protein

structure search.

MD33

33-Room 410, Marriott

Radiation Therapy Optimization:

Algorithms and Biological Effects

Sponsor: Health Applications

Sponsored Session

Chair: Gino Lim, Department Chair, Hari And Anjali Agrawal Faculty

Fellow, Associate Professor, University of Houston, E206, Engr. Bldg 2,

Houston, TX, 77204, United States of America,

ginolim@Central.UH.EDU

1 - Benders Decomposition and an LP-based Heuristic for Selecting

IMRT Treatment Beam Angles

Sifeng Lin, The University of Texas at Austin, 1 University Station

C2200, Austin, TX, 78712, United States of America,

sifenglin@utexas.edu

, Jonathan Bard, Gino Lim

This talk presents two Benders decomposition algorithms and a novel two-stage

integer programming-based heuristic to optimize the beam angle and fluence map

in Intensity Modulated Radiation Therapy planning. The results indicated that

implementing Benders using the lazy constraint usually led to better feasible

solutions than the traditional approach. Moreover, the LP rounding heuristic can

generate good solutions quickly, with further improvement obtained with the

local branching search.

2 - Robust Optimization for Craniospinal Irradiation using Intensity

Modulated Proton Therapy

Li Liao, Research Assistant, University of Houston,

4800 Calhoun Rd, Houston, TX, 77004, United States of America,

lliao5@uh.edu

, Gino Lim, Xiaodong Zhang

Conventional passive scattering proton therapy (PSPT) is an extremely complex

technique for craniospinal irradiation (CSI). In this study, we proposed a robust

intensity modulated proton therapy (IMPT) for CSI. A small dose deviation can be

achieved when ±3 mm mis-alignment errors were applied on field junction for

the robust IMPT plans, whereas this index was more than 40% for PSPT plans. A

simplified dose model was introduced to predict dose deviation in different field

arrangement situation.

MD33