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CCG 943 clinical trial

Radiotherapy

Radiotherapy

Randomised

58 Children

with HGG

Prednisone, Vincristine , Lomustine

5

yrs PFS 46% in RT + CT vs. 26% RT alone

Sposto R et al. J Neurooncol 1989

This benefit was most evident in GBM histology

High grade glioma