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Radiotherapy

Radiotherapy

Randomised

85 Children

with HGG

Prednisone, Vincristine , Lomustine

Finlay JL et al. JCO 1995

8 drugs in 1*

*

vincristine, CCNU, procarbazine, hydroxyurea, cisplatin, mannitol, cytarabine,

dacarbazine, methylprednisolone

CCG 945 clinical trial

CT pre and post-RT

High grade glioma