Chemotherapy and autologous stem cell rescue
Grovas AC et al. Med Pediatr Oncol 1999
Thiotepa, BCNU, and
etoposide
11 Children
with HGG
ASCR
This study was closed early after 5 of the 11 treated. Patients developed significant
pulmonary complications
CCG 9922 study
Focal RT*
*Focal RT
daily — Total dose 54 Gy
2-year PFS rate of 46%