48 / 1544
Phase II study 2005
–
2010
108 patients with cT3-4 rectal cancer treated preoperatively
Radiotherapy (RT): 23 x 2 Gy with IG-IMRT by helical tomotherapy
with daily MVCT scan positioning and without concurrent
chemotherapy
SIB of 0.4 Gy/day on the primary tumor up to a total dose of 55.2
Gy for patients with a narrow CRM on MRI (
≤
2 mm) to maintain
oncological safety
Radiotherapy
5
weeks
5-6 weeks
adjuvant chemotherapy
Late toxicity
Outcome
11
follow-up