1373 / 1674
1.27 (1.04-1.55)
RT
increased
risk
1.17 (0.56-2.44)
1.04 (0.94-1.16)
2.96 (1.17-6.18)
1.34 (1.11-1.61)
1.10 (1.01-1.21)
-
-
-
RT-associated sites
All sites
Subtotal non-RT-associated sites
Subtotal RT-associated sites
Connective tissue
Bones & joints
Pleura
Heart/mediastinum
Lung, bronchus, trachea
Esophagus
RT 23,627
3
16
20
292
1
3
4
186
15
11
226
328
0
2
1
1,102
702
1,430
928
Solid Second Cancers
HR (95% CI)
0.5 1
2
3
4
RT
decreased
risk
Observations Observations
RT 23,627 Non-RT 22,549
HR of Second Solid Cancer comparing
RT treated with non-RT treated
Grantzau et al. Radiotherapy and
Oncology 2013; 106: 42-49