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Examples for real dose‐response curves and effect of random
uncertainty for total dose (EQD2)
Uncertainties
of physical
R=f(D+DD)
t d
R
Patient B
Patient A
fraction dose
R=f(D-DD)
expec e response
R=f(D-+DD)
R=f(D)
R=f(D-DD)
translated to
total dose EQD2
Patient B
D+DD
D DD
expected dose
D
P ti
t A
to uncertainty
in response
probability
-
target
OAR
a en