Increasing OAR dose constraints by reducing uncertainties
20%
30%
D=5 Gy
10%
Same complication rate
predicted for
SD 30% @ 70 Gy EQD2
SD 20% @ 75 Gy EQD2
Clinician could consider relaxing the OAR dose constraint for this case, if it were possible to
decrease large random uncertainties in the workflow!
“Can reduction of uncertainties in cervix cancer brachytherapy potentially
improve clinical outcome?” Nesvacil et al. 2016, submitted to R&O




