809 / 1173
1/03/2016
18
Prostate
•
Brachytherapy is a feasible salvage option for pts with
local recurrences after initial RT for prostate cancer
35
Ramey World J Urol 2013
Prospective studies needed to better define
efficacy and toxicity
Prostate
•
Toxicity fairly high
36
Ramey World J Urol 2013
Study
Number
of patients
Treatment
Modality,dose
a
GU
Grade 1–2
GU
Grade 3–4
GI
Grade 1–2
GI
Grade 3–4
Incontinence
(%)
ED (%)
Fistula
formation
(%)
(%)
(%)
(%)
(%)
Butler et al. [35];
30
Au
198
, 20 Gy
A-37
0
A-13
0
NR
NR
NR
Teh et al. [31]
L-7
L-3
Wong et al. [34]
17
I
125
, 127-139 Gy
53
47
65
6
18
b
NR
0
Pd
103
, 119 Gy
Nguyen et al. [30]
25
I
125
, 137 Gy
NR
20
NR
20
12
NR
13
Lee et al. [26]
21
HDR, 36 Gy/6 fractions
86
14
14
0
0
92
0
Allen et al. [18]
12
I
125
/Pd
103
, 90–112.5 Gy
42
0
0
0
25
NR
0
Lee et al. 27
21
Pd
103
, 90 Gy
29
0
5
0
NR
NR
0
Tharp et al. [32]
7
HDR, 6-9 Gy/2-6 fractions ? 71
29
c
14
0
29
100
0
Aaronson et al. [17]
24
I
125
/Pd
103
, 72 Gy
33
0
8
4
4
NR
0
Burri et al. [20]
37
Pd
103
, 110 Gy
32
8
5
3
5
75
3
I
125
, 135 Gy
Moman et al. [29]
31
I
125
, 145 Gy
A-87
A-3
A-55
A-0
NR
NR
6
L-55
L-19
L-51
L-6
Jo et al. [24]
11
HDR, 22 Gy/2 fractions
‘Low’
0
0
0
0
NR
0