1206 / 1578
Maintained
Neurocognitive
function
Total
(n=1194)
1 tumors
N=455
2-4 tumors
(B) N=531
5-10
tumors
(C) N=208
P
value
B vs C
4 months after SRS
12 months after SRS
24 months after SRS
36 months after SRS
623/662 (94%)
333/366 (91)
120/128 (94)
28/30 (93%)
243/256
(95%)
141/154
(92%)
55/60 (92%)
14/15(93%)
263/284 (93%)
139/152 (91%)
47/48 (98%)
10/11 (91%)
117/
122
(96%)
53/60 (88%)
18/20 (90%)
4/4 (100%)
0.27
0.60
0.20
1.00
•
In long term survivors, decline of Neurocognitive dysfunction
is detectable, but not higher than 10% even in the group of
multiple brain metastases.