1202 / 1578
•
1194 pts;1-10 brain metastases
455 pts 1 metastasis
531 pts 2-4 metastases
208 pts 5-10 metastases
•
Hypothesis :
No difference SRS 5-10 metastases to SRS
2-4 metastases
•
Dose:
22Gy < 4ml
20 Gy 4-10ml
Median OS :
1 tumor
13,9 months (range 12.0-15.6)
2-4 tumors
10.8months(range 9.4-12.4)
5-10 tumors
10.8 months (Range 9.1-12.7)
Prospective Study: