1205 / 1578
Treatment related
adverse events
Total
(n=1194)
1 tumors
N=455
2-4 tumors
(B) N=531
5-10
tumors
(C) N=208
P
value
B vs C
Treatment related
advers events
None
Grade 1 and 2
Grade 3
Grade 4
Grade 5
Had MMSE at baseline
1093 (92%)
69 (6%)
20 (2%)
8 (1%)
4 (<1%)
1132 (95%)
422 (93%)
22(5%)
6(1%)
3(1%)
2(<1%)
430 (95%)
481(91%)
36(7%)
10(2%)
3(1%)
1(<1%)
504 (95%)
190 (91%)
11(5%)
4(2%)
2(1%)
1(<1%)
198 (95%)
0.891
•
Grade 4 and 5 are very rare (less than 1%) in SRS of brain
metastases. They may happen all groups of single-, oligo-,
and multi-metastases