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INFORMS Nashville – 2016

118

5 - Prioritizing Hepatitis C Treatment in U.S. Prisons

Turgay Ayer, Georgia Tech, Atlanta, GA, Boston, MA,

ayer@isye.gatech.edu

, Anthony Bonifonte, Can Zhang, Anne

Spaulding, Jagpreet Chhatwal

High prevalence of HCV in prisons offers a unique opportunity to control the HCV

epidemic. Newest HCV treatments drugs are effective but providing treatment is

outrageously expensive. We propose a restless bandit modeling framework to

support hepatitis C treatment prioritization decisions in U.S. prisons. From the

interpretation of this closed-form expression, we anticipate the performance of

Whittle’s index would degrade as the treatment increases. Using a detailed agent-

based simulation model, we show our proposed policy can significantly improve

overall health outcomes compared with the current practice. Our results shed

light on issues in hepatitis C prioritization: 1) considering remaining sentence

length and injection drug use (IDU) status and liver health state in prioritization

decisions can lead to a performance improvement; 2) when linkage-to-care rate

outside prison is small while treatment capacity in prison system is relatively

large, patients with shorter remaining sentence lengths should be prioritized; and

3) for patients with advanced liver disease, IDUs should not be prioritized unless

their reinfection is very-well controlled.

SD70

Acoustic- Omni

Transportation, General

Contributed Session

1 - Solving The Privately Owned Automated Vehicles

Assignment Problem

Theresia van Essen, Delft University of Technology, Mekelweg 4,

Delft, 2628 CD, Netherlands,

j.t.vanessen@tudelft.nl,

Gonçalo Correia

We propose a new model to study how replacing privately owned non-automated

vehicles with shared automated ones affects travel time, congestion and parking

demand in an urban area. As automated vehicles will reduce the value of travel

time, it is expected that travel time will increase. In addition, congestion is on the

one hand expected to increase because of the empty trips, and on the other hand

expected to decrease because of a reduction in the number of vehicles on the

road. Parking demand is expected to decrease as the utilization of the vehicles will

increase. The model is applied to a case study based on the city of Delft, the

Netherlands.

2 - Developing Interrelated Airport Facilities under Uncertainty:

A Network Flow Formulation

Yanshuo Sun, University of Maryland, 1173 Glenn Martin Hall,

College Park, MD, 20742, United States,

yssun@umd.edu,

Paul Schonfeld

Interactions between user flows and facilities are quite complex in an airport

system. Thus, capacity expansion decisions for these facilities are largely

interrelated. A network flow formulation is proposed for coordinating such

development decisions so that a balanced capacity configuration is likely to be

obtained. The nonlinear congestion effect, which is common in most airport

facilities, is considered and uncertainties in demand and aircraft mix are also

included. The stochastic mixed integer nonlinear program is reduced to a

deterministic mixed integer program and thus solved.

3 - From Trend Spotting To Trend Setting: Modeling The Impact

Of Major Technological And Infrastructural Changes On

Travel Demand

Feras El Zarwi, PhD Candidate, University of California at

Berkeley, 2100 Channing Way, Apt 415, Berkeley, CA, 94704,

United States,

feraselzarwi@gmail.com

Transformative mobility will revolutionize travel and activity behavior but we

should be cautious with how the future is going to play out. This research project

proposes a methodological framework tailored to address impacts of technological

innovation to understand and predict long-range trends in travel behavior. We

integrate hidden markov and discrete choice models to predict long-range trends

in travel behavior as a result of adopting new services. The model is estimated on

a longitudinal travel diary dataset from Santiago, Chile. The proposed quantitative

methods are critical in assessing how policies/strategies can influence trends of

travel behavior to guide transformative mobility.

4 - Using Regression Tree Models To Improve Freeway Incident

Duration Prediction A Comprehensive Case Study In

Maryland Region

Xuechi Zhang, Graduate Research Assistant, University of

Maryland, 0147C Engineering Lab Building, College Park, MD,

20740, United States,

zhangxc90@gmail.com

, Ali Haghani,

Yeming Hao

Timely and accurate prediction of freeway incident duration is not only useful for

providing travelers with re-routing strategies, but can also reduce their in-vehicle

anxiety. This research proposed several regression tree based models to improve

the incident duration prediction accuracy by fusing heterogeneous information,

i.e. incident information, weather and traffic conditions. A comprehensive case

study with real-world data in Maryland Region was conducted to evaluate and

demonstrate the proposed models. Further, practical implications from the case

study were given.

SD71

Electric- Omni

Transportation, Rail

Contributed Session

Chair: Emmanuel Martey, University of Delaware, 302 DuPont Hall,

Newark, DE, 19716, United States,

enmartey@udel.edu

1 - Optimization Techniques For Railways

Srinivasa Prasanna, Professor, IIIT-Bangalore, 26/C, Hosur Road,

Electronics City, Opposite Infosys Technologies, Bangalore,

560100, India,

gnsprasanna@iiitb.ac.in

We present optimization techniques used in portions of the Indian Railway

System, the largest in the world. We present techniques used for timetabling and

investment planning, under large scale demand uncertainty. Many of these

problems are at the scale of grand computational challenges (with 10’000 of trains

and 1000’s of control points), and the talk will present a few pieces of how

portions of this problem can be simplified and made amenable to optimization

techniques (convex/non-convex). Exemplary results will be discussed.

2 - Railway Capacity Analysis And Cyclic, Combined Train

Timetabling And Platforming For A Single Track, Bidirectional

Railway Line

Matthew Petering, University of Wisconsin-Milwaukee, Industrial

and Manufacturing Engineering Dept, Ems E367, Milwaukee, WI,

53201, United States,

mattpete@uwm.edu

, Mojtaba Heydar

We present the literature’s first mixed integer linear program for cyclic train

timetabling and platforming on a single track, bi-directional railway line. There

are T train types and one train of each type is dispatched per cycle. The decisions

to be made include the sequencing of the train types on the main line and the

assignment of train types to station platforms. Two conflicting objectives—

minimizing cycle length and minimizing total train journey time—are considered.

3 - A MIP Model For High-speed Train Platforming Problem With

Route Conflicts Constraints

Gongyuan Lu, Assistant Professor, Southwest Jiaotong University,

111#, 1st Section, Northern 2nd Ring Road, School of

Transportation and Logistics, Chengdu, China,

lugongyuan@swjtu.cn

, Guangyuan Zhang, Yuan Wang

The biggest challenge in solving high-speed train platforming problem (HTPP) is

to route trains without conflicts. Especially in a large multi-yard railway station,

the conflicts between routes and platforms can easily make the scale increase

dramatically. A MIP model aiming at minimize train delay is formulated to

generate flexible train schedule without violating route conflicts. This research

has been applied in largest high-speed train station in Asia.

4 - Predicting Cascading Effects Of Local Disruptions In A Large

Scale Rail Network

Patrick Briest, McKinsey & Co, Kennedydamm 24, Dusseldorf,

40027, Germany,

patrick_briest@mckinsey.com

, Sebastian Albert,

Robin Blöhm, Florian Brummer, Christian Gruß,

Eike-Dennis Rausch

We propose a stochastic simulation model to determine network-wide effects of

locally induced disruptions in a large scale rail system. We extend the model

previously described by Berger et al. to include (A) dynamic diversion routing to

mimic how traffic controllers will try to route trains around disrupted parts of the

network and (B) track capacities and a load-dependent delay component. We

present computational results based on detailed delay distributions extracted from

multiple years of Deutsche Bahn’s operations data and simulation runs using both

current and historic schedules of regional, long-distance and cargo traffic in the

Deutsche Bahn network.

SD70