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INFORMS Nashville – 2016

120

SD86

GIbson Board Room-Omni

Manufacturing IV

Contributed Session

Chair: Ali AlArjani, PhD Candidate, University of Wisconsin -

Milwaukee, 4848 N. Lydell Ave, Apt 141, Milwaukee, WI, 53217,

United States,

alarjan2@uwm.edu

1 - Setting Optimal Planned Leadtimes In A Configure To Order

Manufacturing System

Sjors Jansen, PhD Candidate, Eindhoven University of Technology

(TU/e), P.O. Box 513, Paviljoen E13, Eindhoven, 5600MB,

Netherlands,

s.w.f.jansen@tue.nl

, Zumbul Atan, Ton de Kok,

Ivo Adan

We study the production planning in Configure To Order (CTO) manufacturing

systems. The system consists of multiple stages that converge to one final

assembly stage. Leadtimes per stage are stochastic due to extensive testing at the

end of each stage. Our goal is to determine optimal planned leadtimes for each

stage such that the total expected production costs are minimized. We derive

Newsvendor equations for each individual stage. This set of equations is solved

and the exact optimal planned leadtimes for each stage are obtained. These

equations give an important insight in the dynamics of the system, since they

indicate to what extend a specific stage can be blamed for the lateness of the final

product.

2 - Introduction Of A Motor Assembly Test Bed To Verify

Manufacturing Technology

Jungryul Bae, Korea Institute of Industrial Technology (KITECH),

Seoul, Korea, Republic of,

somanythat@naver.com

, SeHwan Ahn,

YongJu Cho, Chul Kim, Hyunchul Tae

A Testbed is a place of verifying newly developed manufacturing technologies

before apply it in practice. We built a motor-assembly Testbed that comprises

seven connected facilities in a line. We have tested several manufacturing

technologies including simulation, quality management, and IoTs on the Testbed.

In this presentation, we aim to introduce our Testbed and share our experience.

The final goal of the Testbed is to enhance the localization ratio of a convergence

of the IoTs and manufacturing technology.Keywords: Connected Smart Factory

(CSF), Testbed, IoTs, manufacturing technology.

3 - Modeling The Impact Of Product Variety On Inventory: Application

To Strategic Assembly Sequencing And Supply Chain Design

Jeonghan Ko, University of Michigan; Ajou University, 1205 Beal

Ave., Industrial & Operations Engineering, Ann Arbor, MI, 4810,

United States,

jeonghan@umich.edu

, Heng Kuang

This paper models the impact of variety on assembly supply chain design when

limited commonality exists between products. We derive theorems on the impact

of product variety on safety inventory, and provide a measure to approximate the

impact. The theorems and new measure are applied in two problems: optimal

process sequencing and optimal assembly decomposition. We prove that to

prioritize the process with a smaller number of variants will reduce the supply

chain cost no matter the commonality is.

4 - Finite Capacity Material Requirement Planning System For Supply

Chain Network

Benyaphorn Paopongchuang, Sirindhorn International Institute of

Technology, Pathum Thani, 12121, Thailand,

bp322@njit.edu

Benyaphorn Paopongchuang, New Jersey Institute of Technology,

Newark, NJ, 07102, United States,

bp322@njit.edu

, Pisal Yenradee

Available Finite Capacity Material Requirement Planning (FCMRP) systems have

some limitations. They are designed to determine production and purchasing

plans in only one factory not in a multi-level supply chain network. Most systems

lack of optimization capabilities. In addition, they do not manage bottleneck

effectively. The proposed algorithm tries to develop FCMRP system that also

considers finite capacity of some key suppliers and customers.

5 - Similarity Coefficient Model For Solving an Oil Global Facility

Location Problem

Ali AlArjani, PhD Candidate, University of Wisconsin - Milwaukee,

4848 N lydell Ave, Milwaukee, WI, 53217, United States,

alarjan2@uwm.edu

Solve an oil global facility location problem by a new similarity coefficient model

for cluster analysis that model ranks multiple countries and cluster them in

groups each group have similar attributes.

SD91

Davidson Ballroom A-MCC

Joint Session HAS/MSOM-HC: Statistical Decision-

Making with Applications in Healthcare

Sponsored: Manufacturing & Service Oper Mgmt,

Healthcare Operations

Sponsored Session

Chair: Mohsen Bayati, Stanford University, Stanford, CA, United States,

bayati@stanford.edu

Co-Chair: Hamsa Bastani, Stanford University, 10 Comstock Circle,

Apt 304, Stanford, CA, 94305, United States,

hsridhar@stanford.edu

1 - Approximation Methods For Adaptive Clinical Trial Design

John R Birge, University of Chicago,

John.Birge@ChicagoBooth.edu

2 - An Analytics Approach To Designing Drug Therapies For Cancer

John M Silberholz, MIT, Cambridge, MA, 02139, United States,

josilber@mit.edu

, Dimitris Bertsimas

We present a data-driven approach to planning clinical trials and designing novel

drug therapies for metastatic breast cancer (MBC). First, we describe construction

of a large database of MBC clinical trial results and tools to help clinicians

visualize the data. Next, we use statistical models to predict efficacy and toxicity

outcomes of trials before they are run, with implications for selecting between

multiple drug therapies for testing. Finally, we use optimization models to design

novel therapies that strike a balance between maximizing patient outcomes and

learning about new drugs; initial evaluation suggests these models may improve

trial outcomes compared to current practice.

3 - Online Decision-making With High-dimensional Covariates

Hamsa Sridhar Bastani, Stanford University, 10 Comstock Circle,

Apt 304, Stanford, CA, 94305, United States,

hsridhar@stanford.edu,

Mohsen Bayati

Big data has enabled decision-makers to personalize choices based on an

individual’s observed characteristics. We formulate this problem as a multi-armed

bandit with high-dimensional covariates, and present a new efficient algorithm

that provably achieves near-optimal performance. The key step in our analysis is

proving convergence of the LASSO estimator despite non-iid data induced by the

bandit policy. We evaluate our algorithm using a real patient dataset on warfarin

dosing; here, a patient’s optimal dosage depends on her genetic profile and

medical records. Our algorithm outperforms existing bandit methods as well as

physicians to correctly dose a majority of patients.

4 - Estimating Average Treatment Effects In High-dimensional

Observational Studies

Stefan Wager, Stanford University, Stanford, CA, United States,

swager@stanford.edu,

Susan Athey, Guido Imbens

There are many studies where researchers are interested in estimating average

treatment effects and are willing to rely on the unconfoundedness assumption,

which requires that treatment assignment is as good as random conditional on

pre-treatment variables. The unconfoundedness assumption is often more

plausible if a large number of pre-treatment variables are included in the analysis,

but this can worsen the finite sample properties of existing approaches to

estimation. In this paper, we propose a new method for estimating average

treatment effects in high dimensions that achieves the semi-parametric efficiency

bound without requiring any modeling assumptions on the propensity score.

SD92

Davidson Ballroom B-MCC

INFORMS Optimization Society Prize Session

Award Session

Chair: Suvrajeet Sen, University of Southern California, 3715

McClintock Ave, Los Angeles, CA, 90089, United States,

s.sen@usc.edu

1 - Optimization SocietyAwards

Suvrajeet Sen, University of Southern California, 3715 McClintock

Ave, Los Angeles, CA, 90089, United States,

s.sen@usc.edu

The Optimization Society sponsors four awards annually. They are a) the

Khachiyan Prize for lifetime contributions in optimization, b) the Farkas Prize for

exceptional mid-career accomplishments, c) the Young Optimization Researcher

award, and finally, d) the student paper prize competition. These awards are

highly competitive and coveted, and this session is dedicated to congratulating the

winners, and their lasting contributions to optimization. The award winners will

present brief overviews of their prize-winning contributions.

SD86