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INFORMS Nashville – 2016

269

3 - Product Planning With Sensory Customer Requirements:

A Plain Yogurt Case

Leman Esra Dolgun, Anadolu University, Iki Eylÿl Kampusu,

Endustri Muhendisligi Bolumu, Eskisehir, Turkey,

ledolgun@gmail.com,

Gulser Koksal, Elcin Kartal Koc

Customers use vague terms to describe their requirements and perceptions of

sensory products such as yogurt, which makes prioritizing improvements and

setting targets for them difficult. In this study, we propose an improved use of

Quality Function Deployment and Kansei Engineering to overcome such

difficulties, and demonstrate it in a plain yogurt case. Customer needs and

perceptions are assessed by special surveys based on semantic scales. Survey data

are analyzed using hypothesis tests and building logistic regression models.

Targets are suggested by optimizing these models.

4 - A Reformulation-based Interior-point Path-following Method For

Determining Proper Equilibria

Chuangyin Dang, Professor, City University of Hong Kong, Dept of

Systems Eng & Eng Mgmt, 83 Tat Chee Avenue, Kowloon, Hong

Kong,

mecdang@cityu.edu.hk

, Yin Chen

This paper extends an equivalent reformulation of Nash equilibrium to a

specifically defined perturbed game that deforms continuously with an extra

variable. As a result of this extension, we develop an interior-point path-following

method for determining a proper equilibrium. The method numerically follows a

smooth path that starts from any given point in the Euclidean space and ends at a

proper equilibrium. Numerical results further confirm the effectiveness of the

method.

TB15

104E-MCC

Industry Job Search Panel

Invited: INFORMS Career Center

Invited Session

Moderator: Adam McElhinney, Uptake Technologies, Chicago, IL,

United States,

adam.m.mcelhinney@gmail.com

1 - Industry Job Search Panel

Adam McElhinney, Uptake Technologies, Chicago, IL,

United States,

adam.m.mcelhinney@gmail.com

Ever wonder how to make the transition from student to OR, Analytics or Data

Science professional? Or maybe you are an experienced professional looking to

make a career switch. Join the Industry Job Search Panel to hear tips from the

pros. Specifically: 1. Strategies to ensure your skills are aligned with the job

market 2. Tips and tricks for landing and succeeding at the interview 3. How to

interview the interviewer

2 - Panelist

Aly Megahed, IBM Research - Almaden, 150 Palm Valley Blvd APT

2066, San Jose, CA, 95123, United States,

aly.megahed@us.ibm.com

3 - Panelist

Beverly Wright, Cox Communications Inc, 125 Centennial Drive,

Peachtree City, GA, 30269, United States,

Beverly.Wright@scheller.gatech.edu

4 - Panelist

Warren Hearnes, Cardlytics, Lilburn, GA, 30047, United States,

whearnes@hotmail.com

TB16

105A-MCC

Information in Optimization

Sponsored: Optimization, Optimization Under Uncertainty

Sponsored Session

Chair: Eugene Perevalov, Lehigh University, 1, Bethlehem, PA, 18015,

United States,

eup2@lehigh.edu

1 - Outpatient Clinic Scheduling With Heterogeneous Patient

Preference And Resource Uncertainty

Deepak Agrawal, Pennsylvania State University, University Park,

PA, United States,

agrawal.deepankur@gmail.com

, Guodong Pang,

Priyantha Devapriya, Soundar Kumara

Reasons of No-shows and how to stop them, has been focus of the research since

more than a decade. No-show adds up to the increases healthcare waste.

Therefore motivated by this we aim to develop advanced scheduling models

which can reduce No-shows by scheduling appointments at patients’ preferred

day and time with their preferred physicians. Researchers have acknowledged

that each patient may have different priority. Our model considers patient

segments with different priorities to design an efficient yet profitable scheduling

system.

2 - Mutual Information Minimization For Evaluating The Causal

Impact Of Home Care Services On Patient Discharge Disposition

Alexander Nikolaev, University at Buffalo,

anikolae@buffalo.edu

,

Yuan Zhou, Sabrina Casucci, Lei Sun, Li Lin

Recent developments in observational causal inference employ subset selection

algorithms that balance the covariate distributions in the compared groups of

treated and untreated units under study. We present a subset selection approach

that works by minimizing the mutual information (MI) between the covariates

and the treatment variable. This becomes possible thanks to the derived

optimality conditions that tackle the non-linearity of a sample-based MI function.

The resulting algorithm runs in polynomial (close to linear) time, allowing for

treatment effect estimation with large datasets. We proceed to draw causal

insights from hospital readmission data of the UB HOMEBASE project.

3 - Information Acquisition Process: The Quantitative Aspect

Eugene Perevalov, Lehigh University,

eup2@lehigh.edu

The classical Information Theory was able to facilitate significant advances in

information transmission by finding a way of properly describing the quantity of

the form of information existence - the various symbols. On the other hand, to

make similar advances in the process of information acquisition, one would need

to properly understand and describe the quantities associated with the

information itself - its content. We take a step in that direction.

TB17

105B-MCC

Stochastic Sequential Assignment and Planning

Sponsored: Optimization, Optimization Under Uncertainty

Sponsored Session

Chair: Olga Raskina, Juno Therapeutics, Seattle, WA, United States,

olga.raskina@junotherapeutics.com

1 - Stochastic Production Scheduling For Personalized Cancer

Therapy Manufacturing

Olga Raskina, Juno Therapeutics,

olga.raskina@junotherapeutics.com,

Jon Gunther

Juno Therapeutics is a clinical-stage company developing novel cellular

immunotherapies. To manufacture our therapeutic T cell product candidates, we

harvest blood cells from a cancer patient, separate or enrich for the appropriate T

cells, activate the cell, insert the gene sequence for the CAR or TCR construct into

the cell’s DNA, and grow these modified T cells to the desired dose level. The

modified T cells can then be infused into the patient or frozen and stored for later

infusion. We are investing substantially in a process that we believe is

commercially scalable for both CARs and TCRs.

2 - Dynamic Path Assignment For Robotic Bees Under

Collision Control

Felisa Vázquez-Abad, Hunter College,

felisav@hunter.cuny.edu

We study the problem of dynamic routing of robotic bees towards the hive. Due

to uncertainty in position measurements, the stochastic problem cannot ensure

collision-free paths. We study the effects that the algorithm parameters have in

reducing the computational complexity and expected number of collisions. We

explore via experimentation a parallel algorithm for cloud computing as well as

crowd sourcing for estimation. In this manner we seek a faster completion time

reducing collisions and computational complexity.

3 - Multidimensional Birth And Death Models For Biochemical

Modeling With A View To Personalized Medicine

Alexey Nikolaev, CUNY, Hunter College and Graduate Center, New

York, NY, 11232, United States,

anikolaev@gradcenter.cuny.edu

,

Felisa J Vázquez-Abad, Jon Gunther

Chemical reactions can be modeled either using ordinary differential equations,

or continuous time Markov chains. The ODE describes the dynamics of the

concentration of proteins. The multidimensional Birth and Death process

describes the dynamics of the number of particles of proteins. We study an

activator/repressor model that regulates circadian cycles in cells. We show that

the ODE is an exact expectation for the B&D process, under some regimes. For

other regimes we apply a novel technique of Taboo kernels. This methodology has

potential to predict malfunctions and to identify treatment.

TB17