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INFORMS Nashville – 2016

272

4 - A Continuous Time Stochastic Model To Optimize Blood Pressure

Treatment Decisions

Anthony Bonifonte, Georgia Institute of Technology,

ABonifon@gatech.edu

, Turgay Ayer, Ben Haaland, Peter Wilson

Antihypertensive drug treatment can control elevated blood pressure and reduce

the risk of future cardiovascular outcomes. We develop a data-driven stochastic

model of blood pressure progression that generalizes Brownian motion by

modeling the change in blood pressure per unit time as a Gaussian mixture

distribution. This model addresses the question of what thresholds at which to

initiate antihypertensive treatment and the optimal intensity. Our main finding is

initiation and intensity decisions depend jointly on systolic and diastolic pressure.

The methods are generalizable to other chronic diseases with continuous valued

measurements.

5 - Designing Effective Vaccine Administration Practices

Gizem Sultan Nemutlu, PhD Candidate, University of Waterloo,

Faculty of Engineering University of Waterloo, Carl A. Pollock Hall

3654 200 University Avenue West, Waterloo, ON, N2L 3G1,

Canada,

gsnemutlu@uwaterloo.ca

, Fatih Safa Erenay,

Osman Yalin Ozaltin

Childhood vaccine wastage due to limited shelf-life of opened vials is still high in

developing countries. Our research shows that open vial wastage can be

significantly reduced by keeping vaccine stocks in different size vials, and

dynamically deciding what size of vial to use next and/or when to terminate daily

vaccination services. We develop a discrete-time MDP model maximizing demand

coverage. We analyze the structural properties of the optimal strategies and show

that the proposed model can help decision makers in determining the best vial-

size combinations and optimal inventory levels.

TB24

109-MCC

Analytics in Evidence-Based Practice (EBP)

Sponsored: Health Applications

Sponsored Session

Chair: John Zaleski, Bernoulli Health, 4801 S. Board Street, Suite 120,

Philadelphia, PA, 19112, United States,

jzaleski@bernoullihealth.com

1 - Clinical Applications Of Data Analytics: A Survey

Amy Harris, Middle Tennessee State University,

amy.harris@mtsu.edu

Increasing volumes and varieties of clinical data and growing interest in analytics

has created opportunities for healthcare organizations to study and address

clinical problems. Experience gained is often employed to improve care and,

where successful, results are published in academic journals. This presentation

surveys the literature and explores which types of analytics are most popular and

how healthcare organizations use data analytics to inform clinical practice.

2 - The Use Of Kalman Filtering In Alarm Management Studies

John Zaleski, Bernoulli Enterprise Inc,

jzaleski@bernoullihealth.com

Vitals signs monitoring in high acuity environments are often the source of alarms

and notifications to care providers. In this presentation, the author demonstrates

the use of a Kalman filtering technique that has been used in the identification of

alarm limit thresholds for capnography monitoring of patients in the medical

surgical environment post-operatively.

3 - The State Of Digital Marketing In The Healthcare Industry

Brian Harris, Lima Consulting,

bharris@limaconsulting.com

Digital marketing technologies and web analytics have opened new opportunities

to provide actionable analysis to decision makers. However, many analysts

struggle with inconsistent or questionable data due to failed or sub optimal

deployments of these technologies. This study examines two million pages across

websites of hundreds of the world’s largest healthcare companies to provide

insights on the relative health of digital marketing and web analytics across

multiple sectors. It also provides practical advice for analysts seeking to improve

the quality and veracity of their web analytics data.

4 - Consistent Staffing For Long-term Care Through On-call Pools

Vincent W. Slaugh, Assistant Professor, Cornell University,

Ithaca, NY, 14850, United States,

vslaugh@cornell.edu,

Alan Scheller-Wolf, Sridhar R Tayur

Nursing home managers have increasingly emphasized consistency of care — i.e.,

minimizing the number of different nurse aides who care for each resident — but

have struggled with this goal due to nurse aide absences before the start of each

shift. We provide structural and numerical results for the relationship between

the number of aides in an on-call pool, on-call pool rules, staffing costs, and

consistency level. We also demonstrate that using part-time aides can actually

improve consistency of care if their on-call pool participation rate is sufficiently

high.

TB25

110A-MCC

Scheduling and Contracts

Invited: Project Management and Scheduling

Invited Session

Chair: Nicholas G Hall, Ohio State University, Columbus, OH, United

States,

hall.33@osu.edu

1 - Multitasking Via Alternate And Shared Processing: Algorithms

And Complexity

Chung-Lun Li, The Hong Kong Polytechnic University,

chung-lun.li@polyu.edu.hk,

Nicholas G Hall, Joseph Leung

This work is motivated by disruptions that occur when jobs are processed by

humans, rather than by machines. E.g., humans may become tired, bored, or

distracted. We present two scheduling models with multitasking features, which

aim to mitigate the loss of productivity in such situations. The first model applies

“alternate period processing” and aims either to allow workers to take breaks or

to increase workers’ job variety. The second model applies “shared processing”

and aims to allow workers to share a fixed portion of their processing capacities

between their primary tasks and routine activities. For each model, we consider

several widely studied and practical classical scheduling objectives.

2 - Scheduling To Minimize Energy Cost

Marc Posner, The Ohio State University,

posner.1@osu.edu

,

Nicholas G Hall

While scheduling is an effective way to improve energy efficiency in

manufacturing, optimal scheduling becomes more complicated when energy costs

vary. Our machine has discretely variable speeds, and increased energy usage is

incurred at faster machine speeds. Three alternative scenarios about the time at

which the machine can change speed are considered. In each scenario, we study

the problem of minimizing total energy cost, subject to the completion of work by

a given date. We describe efficient algorithms for these problems where possible,

and also identify limits to their solvability.

3 - Analysis Of A Procurement Game With Option Contracts

Bo Chen, University of Warwick, Coventry, United Kingdom,

b.chen@warwick.ac.uk,

Edward James Anderson, Lusheng Shao

When a firm faces an uncertain demand, it is common to procure supply using

some type of option in addition to spot purchases. A typical version of this

problem involves capacity being purchased in advance, with a separate payment

made that applies only to the part of the capacity that is needed. We address such

a problem by formulating it as a procurement game, in which competing suppliers

choose a reservation price and an execution price for blocks of capacity, and the

buyer, facing known distributions of demand and spot price, needs to decide

which blocks to reserve.

4 - Scheduling Crash Tests At Ford With Sequencing Restrictions

And Capacity Constraints

Yuhui Shi, University of Michigan, 2212 Glencoe Hills Drive, Apt

11, Ann Arbor, MI, 48108, United States,

yuhuishi@umich.edu

,

Amy Cohn, Marina Alex Epelman

We present the problem of scheduling crash tests at Ford Motor for new vehicle

model development. In this problem, we assume performing crash tests requires

prototype vehicles as well as other limited supporting resources such as testing

facilities and engineers. We show how to solve the problem subject to these

resource constraints by using various decomposition methods.

TB26

110B-MCC

Combinatorial Auction Pricing

Invited: Auctions

Invited Session

Chair: Benjamin Lubin, Boston University, Boston, MA, United States,

blubin@bu.edu

1 - Adaptive-price Combinatorial Auctions

Benjamin Lubin, Boston University,

blubin@bu.edu

This work introduces and implements an iterative combinatorial auction that aims

to achieve both high efficiency and fast convergence without prior restrictions on

the valuation domain. Our auction uses polynomial prices, which price

combinations of items beyond just single items, and gradually extends price

expressivity as the rounds progress. We also propose a heuristic approach to

winner determination to ensure the auction scales. An experimental evaluation

shows that our auction is competitive with bundle-price auctions in regimes

where these excel, namely multi-minded valuations, but also performs well in

regimes favorable to linear prices, such as valuations with pairwise synergy.

TB24