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Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
539-P
os
B
oard
B319
ELECTRON-CONFORMATIONAL TRANSFORMATIONS IN
NANOSCOPIC RYR2 CHANNELS GOVERN BOTH THE HEART’S
CONTRACTION AND BEATING.
Alexander Moskvin
, Alexander
Ryvkin, Nikolay Zorin, Kirill Soulim, Bogdan Yaparov, Olga Solovyova,
Vladimir Markhasin
540-P
os
B
oard
B320
MG56, A MEMBER OF THE MBOAT FAMILY OF PROTEINS,
REGULATES INTRACELLULAR CALCIUM SIGNALING IN
STRIATED MUSCLE.
Matthew Sermersheim
, Xinyu Zhou, Ki Ho
Park, Pei-Hui Lin, Jacob Yount, Wayne Chen, Miyuki Nishi, Hiroshi
Takeshima, Jianjie Ma
541-P
os
B
oard
B321
CISPLATIN-INDUCED CACHEXIA IN RATS CAUSES
ALTERATIONS IN SKELETAL MUSCLE CALCIUM
HOMEOSTASIS. Elena Conte, Adriano Fonzino, Sabata Pierno, Giulia
Maria Camerino, Maria Cannone, Kejla Musaraj, Laura Rizzi, Elena
Bresciani, Antonio Torsello, Diana Conte,
Antonella Liantonio
542-P
os
B
oard
B322
STIM1 ENHANCES SR CA
2+
CONTENT THROUGH INHIBITING
PHOSPHOLAMBAN IN RAT VENTRICULAR MYOCYTES.
Guiling Zhao
, Didier X. P. Brochet, Tianyu Li, Paul Rosenberg, W.
Jonathan Lederer
543-P
os
B
oard
B323
REGULATION OF CALCINEURIN BY CALCIUM-BINDING
COUSINS. Lisa D. Weaver, Brandon R. Uribe, Maria F. Núñez
Hernandez, Michael C. Rendleman, Sean A. Klein, Susan E. O’Donnell,
Madeline A. Shea
544-P
os
B
oard
B324
IDENTIFY THE BINDING INTERFACE BETWEEN CALSENILIN
AND PRESENILIN 1 C-TERMINAL FRAGMENT.
Khoa N. Pham
,
Jaroslava Miksovska
545-P
os
B
oard
B325
ROLE OF MITOCHONDRIAL CA
2+
UNIPORTER IN RADIATION-
INDUCED CELL DAMAGE.
Xibao Liu
, Baijuan Gong, Hwei Ling
Ong, Kwong Tai Cheng, Madesh Muniswamy, Indu S. Ambudkar
546-P
os
B
oard
B326
DIVERSITY OF MITOCHONDRIAL CA (
2+
) SIGNALING:
EVIDENCE FROM GENETICALLY ENCODED PROBES.
Xiaohua Zhang
, Naohiro Yamaguchi, Lars Cleemann, Martin Morad
547-P
os
B
oard
B327
ANALYSIS OF ATP PRODUCTION EFFICIENCY OF BEAT-
TO-BEAT CALCIUM FLUCTUATIONS IN CARDIAC
MITOCHONDRIA.
Sangeeta Shukla
, W. Jonathan Lederer, M. Saleet
Jafri
548-P
os
B
oard
B328
IN VIVO TEMPERATURE SENSITIVITY OF THE CALCIUM
AFFINITY OF FLUO-5F AND MAG-FLUO4.
Brian M. Hagen
, Joseph
P.Y. Kao, W, Jonathan Lederer
549-P
os
B
oard
B329
A NOVEL RED FLUORESCENCE CALCIUM INDICATOR FOR
FUNCTIONAL ANALYSIS OF GPCRS AND CALCIUM CHANNEL
TARGETS. Qin Zhao, Haitao Guo, George Yi,
Jinfang Liao
, Zhenjun
Diwu
550-P
os
B
oard
B330
COUPLING INTERACTIONS OF THE DIMERIC SOAR UNIT OF
STIM1 WITH ORAI1 CHANNELS.
Yandong Zhou
, Xizhuo Wang,
Xianming Wang, Natalia A. Loktionova, Xiangyu Cai, Xiangyu Cai,
Youjun Wang, Donald L. Gill
551-P
os
B
oard
B331
TRANSLOCATION BETWEEN PI(4,5)P
2
-POOR AND PI(4,5)
P
2
-RICH MICRODOMAINS DURING STORE DEPLETION
DETERMINES STIM1 CONFORMATION AND GATING OF
ORAI1.
Shmuel Muallem
, Jozsef Maléth, Seok Choi, Malini Ahuja
Cardiac, Smooth, and Skeletal Muscle
Electrophysiology I (Boards B332-B347)
552-P
os
B
oard
B332
DIFFERENTIAL EFFECTS OF ANTIARRHYTHMIC DRUGS
VERNAKALANT AND FLECAINIDE ON HUMAN TWO-PORE-
DOMAIN K
+
CHANNELS.
Dierk Thomas
, Claudia Seyler, Patrick A.
Schweizer, Hugo A. Katus
553-P
os
B
oard
B333
CLASSIFYING THE ELECTROPHYSIOLOGICAL EFFECTS
OF CHRONOTROPIC DRUGS ON HUMAN INDUCED
PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES
USING VOLTAGE SENSITIVE DYES AND SUPERVISED
MACHINE LEARNING.
Christopher M. Heylman
, Rupsa Datta,
Bruce R. Conklin, Steven C. George, Enrico Gratton
554-P
os
B
oard
B334
SPARFLOXACIN, A FLUOROQUINOLONE ANTIBIOTIC, SLOWS
INACTIVATION OF L-TYPE CA
2+
CURRENT IN NEONATAL RAT
VENTRICULAR MYOCYTES.
Jae Gon Kim
, Sang Woong Park, Hun
Ji Kim, Hana Cho, Young Min Bae
555-P
os
B
oard
B335
ON-CHIP QUASI-
IN VIVO
PREDICTIVE CARDIOTOXICITY
ASSAY USING SPATIOTEMPORAL FLUCTUATION
MEASUREMENT ON HUMAN CARDIOMYOCYTE CELL-
NETWORK.
Fumimasa Nomura
, Tomoyuki Kaneko, Hideyuki
Terazono, Kenji Yasuda
556-P
os
B
oard
B336
LABEL-FREE HIGH-THROUGHPUT CARDIOTOXICITY ASSAYS
USING COMBINED IMPEDANCE AND EXTRACELLULAR FIELD
POTENTIAL MEASUREMENTS. Corina T. Bot, Sonja Stoelzle-Feix,
David R. Guinot, Ulrich Thomas, Ulrich Thomas, Leo Doerr, Matthias
Beckler, George Okeyo, Joerg Oestreich,
Rodolfo J. Haedo
, Michael
George, Niels Fertig
557-P
os
B
oard
B337
A NOVEL CLASSIFICATION METHOD WITH SUPERIOR
PREDICTION OF DRUG ARRHYTHMIA RISK.
Megan A. Cummins
, Eric A. Sobie
558-P
os
B
oard
B338
ELECTROPHYSIOLOGY OF CARDIAC TISSUE SLICES BEFORE,
DURING, AND AFTER STRETCH. Ken Wang, Razik Mu-u-min,
Derek Terrar, David GJ Gavaghan, Peter Kohl,
Christian Bollensdorff
559-P
os
B
oard
B339
DUAL SPIKES OF CATECHOLAMINE RELEASES FROM
SYMPATHETIC NERVES IN RODENT HEART SLICES
FOLLOWING HYPOXIA-REPERFUSION AS RECORDED BY A
NOVEL ELECTROCHEMICAL METHOD. Bing Liu, Shu Guo, Jing
L
ǚ
, Xinjiang Kang, Yun Xiu, Jingli Gu, Yu Mu, Qian Lei, Bin Liu, Kun
Liu, Lihuan Li, Changhe Wang, Jimin Cao,
Zhuan Zhou
560-P
os
B
oard
B340
ELECTRONIC EXPRESSION OF IK1 IN HUMAN INDUCED
PLURIPOTENT STEM CELL DERIVED CARDIOCYTES REVEALS
ATRIAL VS VENTRICULAR SPECIFIC PROPERTIES. Aaron D.
Kaplan, Glenna C.L. Bett,
Randall L. Rasmusson