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43

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

S

A

T

U

R

D

A

Y

F

R

I

D

A

Y

U

N

D

A

Y

659-P

os

B

oard

B439

MITOCHONDRIAL ABNORMALITIES IN A MOUSE CPVT

MODEL WITH RYR2 LOSS-OF-FUNCTION MUTATION. V.

Ramesh Iyer,

Manuela Lavorato

, Yang-Ting Zhao, Hector H. Valdivia,

Clara Franzini - Armstrong

660-P

os

B

oard

B440

WNT SIGNALING SELECTIVELY INHIBITS SODIUM

CHANNELS IN CARDIAC MYOCYTES.

Wenbin Liang

, Eduardo

Marbán

661-P

os

B

oard

B441

THE PHYSIOLOGICAL RELEVANCE OF INTERACTIONS

BETWEEN CMYBP-C AND ACTIN STUDIED IN A TRANSGENIC

MOUSE MODEL.

Sabine J. van Dijk

, Kristina L. Bezold, Samantha P.

Harris

662-P

os

B

oard

B442

THE HCM MUTATION L348P IN CMYBP-C ENHANCES THIN

FILAMENT ACTIVATION THROUGH TROPOMYOSIN SHIFT. Ji

Young Mun, Robert W. Kensler, Samantha P. Harris,

Roger Craig

663-P

os

B

oard

B443

CROSSBRIDGE ARRANGEMENT IN CARDIAC THICK

FILAMENTS ISOLATED FROM CMYBP-C PHOSPHOMIMETIC

MICE.

Robert W. Kensler

, Roger Craig, Richard L. Moss

Kinesins, Dyneins, and Other

Microtubule-based Motors

(Boards B444-B471)

664-P

os

B

oard

B444

DECRYPTING THE STRUCTURAL, DYNAMIC AND ENERGETIC

BASIS OF KINESIN INTERACTING WITH TUBULIN DIMER

IN THREE ATPASE STATES BY ALL-ATOM MOLECULAR

DYNAMICS SIMULATION.

Wenjun Zheng

, Srirupa Chakraborty

665-P

os

B

oard

B445

A NEW MECHANISM OF KINESIN MOLILITY: CONVERSION

OF RANDOM MOTION TO DIRECTIONAL MOTION WITH

RATCHET STRUCTURE.

Ya-chang Chou

666-P

os

B

oard

B446

QUANTIFICATION OF IFT-DYNEIN DYNAMICS IN

C.ELEGANS.

Jona Mijalkovic

, Bram Prevo, Felix Oswald, Pierre JJ

Mangeol, Erwin JG Peterman

667-P

os

B

oard

B447

3D REAL-TIME ORBITAL TRACKING IN ZEBRAFISH EMBRYOS:

HIGH SPATIOTEMPORAL ANALYSIS OF MITOCHONDRIAL

DYNAMICS IN NEURONS.

Fabian Wehnekamp

, Gabriela Plucińska,

Thomas Misgeld, Don C. Lamb

668-P

os

B

oard

B448

MOTOR COORDINATION IN LONG-DISTANCE TRANSPORT

IN AXONS. Praveen Chowdary, Daphne Che,

Bianxiao Cui

669-P

os

B

oard

B449

PHOSPHORYLATION REGULATES THE MOTILE PROPERTIES

OF A MITOTIC KINESIN.

Ofer Shapira

, Larisa Gheber

670-P

os

B

oard

B450

cpow mid

-

career

travel awardee

MECHANO-CHEMICAL MODEL FOR THE STEPPING OF

CYTOPLASMIC DYNEIN.

Andreja Šarlah

, Andrej Vilfan

671-P

os

B

oard

B451

DYNACTIN FUNCTIONS AS BOTH A DYNAMIC TETHER AND

BRAKE DURING DYNEIN-DRIVEN MOTILITY.

Swathi Ayloo

,

Jacob E. Lazarus, Aditya Dodda, Mariko Tokito, E Michael Ostap, Erika

Holzbaur

672-P

os

B

oard

B452

TOWARDS SIMULATION OF VIRTUAL CELLS: THE KINESIN-

MICROTUBULE MOLECULAR MOTOR.

Srayanta Mukherjee

,

Jeffrey Skolnick

673-P

os

B

oard

B453

education

travel awardee

KINESIN-2’S ROLE IN INTRACELLULAR CARGO

TRANSPORT: NAVIGATING THE COMPLEX MICROTUBULE

LANDSCAPE.

Gregory Hoeprich

, William Hancock, Christopher

Berger

674-P

os

B

oard

B454

COOPERATIVE TRANSPORT BY POPULATIONS OF FAST AND

SLOW KINESINS UNCOVERS NOVEL FAMILY-DEPENDENT

MOTOR CHARACTERISTICS IMPORTANT FOR IN VIVO

FUNCTION. Göker Arpağ, Shankar Shastry, William O. Hancock,

Erkan Tüzel

675-P

os

B

oard

B455

KINESIN REGULATION DYNAMICS THROUGH CARGO

DELIVERY, A SINGLE MOLECULE INVESTIGATION.

Anthony P. I. Kovacs

, Jonathan M. Kessler, Huawen Lin, Susan K.

Dutcher, Yan Mei Wang

676-P

os

B

oard

B456

SENSITIVITY OF MULTIPLE-KINESIN TRANSPORT TO

MICROTUBULE LATTICE DEFECTS. K M Rifat Faysal, Stephen J.

King,

Jing Xu

677-P

os

B

oard

B457

CHARACTERIZING THE ALLOSTERIC EFFECT OF

NUCLEOTIDE AND INHIBITOR BINDING TO THE KINESIN

MOTOR DOMAIN.

Guido Scarabelli

, Barry J. Grant

678-P

os

B

oard

B458

EFFECT OF FORCE AND DISCRETE STEP-SIZE ON THE

VELOCITY DISTRIBUTION OF PROCESSIVE MOLECULAR

MOTORS.

Huong T. Vu

, Shaon Chakrabarti, Michael Hinczewski, D.

Thirumalai

679-P

os

B

oard

B459

DEVELOPMENT OF PHOTO-CONTROLLED MOLECULAR

SHUTTLE UTILIZING ATP DRIVEN MOTOR KINESIN.

Naozumi Numata

, Kazunori Kondo, Shinsaku Maruta

680-P

os

B

oard

B460

STUDY OF PHOSPHO-REGULATION OF A MITOTIC KINESIN

USING A DIRECTED EVOLUTION APPROACH.

Alina Goldstein

,

Nurit Siegler, Liam Holt, Leah Gheber

681-P

os

B

oard

B461

TRANSPORT BY A KINESIN IN THE PRESENCE OF MAGNETIC

NANOPARTICLES.

Ehsan Mirzakhalili

, Eleni Gourgou, Bogdan

Epureanu

682-P

os

B

oard

B462

KINETIC CHARACTERIZATION OF RICE PLANT SPECIFIC

KINESIN E11 USING FLUORESCENT ATP ANALOGUE.

Hironobu Taniguchi

, Nozomi Umezu, Shinsaku Maruta