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42
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
636-P
os
B
oard
B416
PKA REDUCES THE RAT AND HUMAN K
CA
3.1 CURRENT,
CAM BINDING AND CA
2+
SIGNALING, WHICH REQUIRES
SER332/334 IN THE CAM-BINDING C TERMINUS.
Raymond Wong
, Lyanne C. Schlichter
637-P
os
B
oard
B417
CARDIAC SODIUM CHANNEL: ACTIVATION BY CAM
INVOLVES A NAV1.5-NAV1.5 INTERACTION. Sandra B. Gabelli,
Agedi Boto, Victoria Halpernin, Mario A. Bianchet, Federica Farinelli,
Srinivas Aripirala,
Jesse B. Yoder
, Jean Jakoncic, Gordon F. Tomaselli,
Mario Amzel
638-P
os
B
oard
B418
CALMODULATION OF VOLTAGE-GATED CALCIUM
CHANNELS BY BLUE LIGHT.
Jacqueline Niu
, Manu Ben-Johny, Paul
J. Adams, David T. Yue
639-P
os
B
oard
B419
PEGYLATED CHOLESTEROL AND METHYL-BETA-
CYCLODEXTRIN ARE MODULATORS OF L-TYPE CALCIUM
CHANNEL CURRENT AND DECREASE MEMBRANE
CAPACITANCE IN VASCULAR SMOOTH MUSCLE CELLS.
Rikuo Ochi
, Sachin A. Gupte
640-P
os
B
oard
B420
NMDA RECEPTOR INHIBITION OF L-TYPE CALCIUM
CHANNELS VIA ER CALCIUM DEPLETION AND ACTIVATION
OF STIM1 IN CULTURED HIPPOCAMPAL NEURONS.
Philip J. Dittmer
, Mark L. Dell’Acqua, William A. Sather
641-P
os
B
oard
B421
DEFINING POST AS A MODULATOR OF STIM1 FUNCTION
DURING T CELL ACTIVATION.
Christina Go
, Robert Hooper,
Joseph Kedra, Jonathan Soboloff
642-P
os
B
oard
B422
education
travel awardee
THE SIGMA1 RECEPTOR COMPETES WITH STIM1 TO BIND
ORAI1 TO REGULATE STORE OPERATED CALCIUM ENTRY
(SOCE).
Shyam Srivats
, Dilshan Balasuriya, Mathias Pasche, Robert
Vistal, Colin W. Taylor, Mike J. Edwardson, Ruth D. Murrell-Lagnado
643-P
os
B
oard
B423
FUNCTIONAL INTERACTION OF AN ORAI1 PORE RESIDUE
WITH THE INACTIVATION DOMAIN OF STIM1.
Franklin M. Mullins
, Richard S. Lewis
644-P
os
B
oard
B424
STIM1 BINDING TO BOTH THE N’ AND C’ TERMINI OF ORAI1
IS CRITICAL FOR GATING OF CRAC CHANNELS.
Raz Palty
,
Cherise Stanley, Ehud Isacoff
645-P
os
B
oard
B425
CLUSTERING OF INWARD RECTIFIER POTASSIUM CHANNELS
IN A PIP2-CONTAINING MEMBRANE: A MOLECULAR
DYNAMICS SIMULATION STUDY.
Anna L. Duncan
, Heidi Koldsø,
Mark S. P. Sansom
646-P
os
B
oard
B426
DIRECT CONTACTS OF K
+
IONS IN THE SELECTIVITY FILTER
ENABLE THE HIGH CONDUCTANCE OF K
+
CHANNELS.
Chen Song
, David A. Köpfer, Tim Gruene, George M. Sheldrick, Mark S.
P. Sansom, Ulrich Zachariae, Bert L. de Groot
647-P
os
B
oard
B427
cpow
travel awardee
EVOLUTIONARY DIVERSITY OF PROTEIN NANODOMAINS
WITHIN MAMMALIAN SPERM.
Melissa R. Miller
, Sam J. Kenny,
Steven A. Mansell, Ke Xu, Polina Lishko
Cardiac Muscle Regulation I
(Boards B428-B443)
648-P
os
B
oard
B428
A FRET-BASED ASSAY FOR MONITORING ACTIONS OF
CALCIUM SENSITIZERS ON THE THIN FILAMENT.
Maria E. Moutsoglou
, Gi-Ho Kim, Christopher Solis-Ocampo, John M.
Robinson
649-P
os
B
oard
B429
SPFRET REVEALS THE MECHANISM OF MYOSIN-DEPENDENT
ACTIVATION OF TROPONIN WITHIN REGULATED ACTION
FILAMENTS.
Gi-Ho Kim
, Maria E. Moutsoglou, Christopher Solis
Ocampo, John M. Robinson
650-P
os
B
oard
B430
BRIDGING INTEGRATOR 1 (BIN1) INITIATES T-TUBULE
GROWTH DURING CARDIAC DEVELOPMENT AND
DISEASE.
David B. Lipsett
, Michael Frisk, Neha Singh, Jan Magnus
Aronsen, William Marszalec, Ole M. Sejersted, Ivar Sjaastad, J. Andrew
Wasserstrom, Geir Christensen, William E. Louch
651-P
os
B
oard
B431
CHARACTERIZING PROTEIN BINDING OF PHOSPHOLAMBAN
TO SERCA USING CHEMICAL CROSS-LINKING.
Vidhya Sivakumaran
, Nikolai Smolin, Seth Robia
652-P
os
B
oard
B432
TOAC SPIN LABEL CONFORMATION RESOLVED
BY MD SIMULATION OF MEMBRANE-BOUND
PHOSPHOLAMBAN.
Andrew Reid
, Jesse McCaffrey, Christine Karim,
Bengt Svensson
653-P
os
B
oard
B433
USING MOLECULAR DYNAMICS SIMULATIONS TO
INTERPRET FLUORESCENCE AND EPR DATA ON LABELED
SERCA AND PHOSPHOLAMBAN.
Bengt Svensson
, Xiaoqiong Dong,
Karl J. Petersen, Zachary M. James, Jesse E. McCaffrey, Howard S. Young,
David D. Thomas
654-P
os
B
oard
B434
PHOSPHOLAMBAN PHOSPHORYLATION ALTERS ITS
CONFORMATIONAL EQUILIBRIUM TO REGULATE SERCA
ACTIVITY.
Leanna McDonald
, Gianluigi Veglia
655-P
os
B
oard
B435
ATOMIC-LEVEL CHARACTERIZATION OF THE
INHIBITION MECHANISM OF THE CALCIUM PUMP BY
PHOSPHOLAMBAN.
L. Michel Espinoza-Fonseca
, Joseph M. Autry,
G. Lizbeth Ramírez-Salinas, David D. Thomas
656-P
os
B
oard
B436
NOVEL ROLES OF GQ-DEPENDENT SIGNAL TRANSDUCTION
FOR CARDIAC PACEMAKING AND CARDIAC IMPULSE
PROPAGATION STUDIED BY GQ-KO AND A DREADD. Elisabeth
Kaiser, Laura Schröder, Kathrina Wiesen, Jürgen Wess, Qinghai Tian, Lars
Kaestner,
Peter Lipp
657-P
os
B
oard
B437
THE LARGE SCALE TRANSCRIPTOME ANALYSIS OF MOUSE
SINOATRIAL NODE (SAN).
Yosuke Okamoto
, Kirill V. Tarasov, Bruce
D. Ziman, Joonho Lee, Edward G. Lakatta
658-P
os
B
oard
B438
A SIMPLE REGULATION OF CARDIOMYOCYTE
EXCITABILITY.
Karni S. Moshal