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39

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

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561-P

os

B

oard

B341

NORMALIZATION OF ACTION POTENTIAL PROPERTIES IN

HUMAN INDUCED PLURIPOTENT STEM CELL DERIVED

CARDIOCYTES BY ELECTRONIC EXPRESSION OF IK1. Aaron D.

Kaplan, Agnieszka Lis, Randall L. Rasmusson,

Glenna C L Bett

562-P

os

B

oard

B342

ACTIVATION OF CA

2+

-DEPENDENT CATION CURRENT BY

FLUID SHEAR FORCE IN ATRIAL MYOCYTES. Min-Jeong Son,

Joon-Chul Kim

, Ju Chen, Sun-Hee Woo

563-P

os

B

oard

B343

STIM1 INCREASES CA

2+

STORES IN THE SARCOPLASMIC

RETICULUM OF ADULT FELINE VENTRICULAR

MYOCYTES.

Constantine Troupes

, Steven Houser

564-P

os

B

oard

B344

REGIONAL HETEROGENIETY OF THE INWARDLY

RECTIFYING POTASSIUM CURRENT IN THE CANINE

HEART.

Brian Panama

, Tanya Zeina, Lini Thomas, Robert Goodrow,

Vladislav Nesterenko, Jacqueline Treat, Jonathan Cordeiro

565-P

os

B

oard

B345

TRANSIENT OUTWARD K

+

CURRENT UNDERLIES

HETEROGENEITY OF ACTION POTENTIAL DURATION AND

EARLY AFTERDEPOLARIZATION FROM RIGHT VENTRICLE IN

TRANSGENIC RABBIT MODEL OF LONG QT TYPE 1.

Bum-Rak Choi

, Weiyan Li, Dmitry Terentyev, Colin Rees, Radmila

Terentieva, Taeyun Kim, Xuwen Peng, Zhilin Qu, Alain Karma, Gideon

Koren

566-P

os

B

oard

B346

ACTION POTENTIAL REPOLARIZATION IN EQUINE

HEARTS.

Kirstine Calloe

, Philip J. Pedersen, Maria de los Angeles

Tejada, Kristian L. Poulsen, Søren Grubb, Rikke Buhl, Dan A. Klaerke

567-P

os

B

oard

B347

OVEREXPRESSION OF ADENYLYL CYCLASE 8 (AC8) IN MICE

INCREASES INTRINSIC HEART RATE (IHR) AND REDUCES

HEART RATE VARIABILITY (HRV), AND DETACHES HR AND

HRV FROM AUTONOMIC MODULATION.

Michael G. Matt

,

Ismayil Ahmet, Oliver Monfredi, Kenta Tsutsui, Edward G. Lakatta

Biopolymers in Vivo (Boards B348-B362)

568-P

os

B

oard

B348

A SENSOR FOR QUANTIFICATION OF MACROMOLECULAR

CROWDING IN LIVING CELLS.

Arnold J. Boersma

, Boqun Liu, Bert

Poolman

569-P

os

B

oard

B349

DESOLVATION ENERGY: A RATIONALE FOR CHANGES IN

BINDING AFFINITY AS MEASURED BY ITC.

Daryl K. Eggers

,

Jennifer M. Le, Duc N. Pham, Nhi T. Nham, Frankie A. Contreras

570-P

os

B

oard

B350

RAPIDLY INDUCIBLE DE NOVO SYNTHESIS OF HYDROGELS

IN LIVING CELLS.

Takanari Inoue

571-P

os

B

oard

B351

EXCLUDED VOLUME EFFECTS INSIDE THE LIVING

CELL.

David Gnutt

, Mimi Gao, Oliver Brylski, Matthias Heyden, Simon

Ebbinghaus

572-P

os

B

oard

B352

MACROMOLECULAR CROWDING IN THE CYTOSOL:

UNDERAPPRECIATED OR OVERESTIMATED?

Joost Groen

,

David Foschepoth, Arnold J. Boersma, Hiromi Imamura, Hans A. Heus,

Wilhelm T.S. Huck

573-P

os

B

oard

B353

THERMODYNAMICS AND KINETICS OF MULTI-PROTEIN

BINDING IN CROWDED ENVIRONMENTS.

Youngchan Kim

,

Jeetain Mittal

574-P

os

B

oard

B354

REAL-TIME TRANSCRIPTION INITIATION BY E.COLI RNA

POLYMERASE IN VITRO AND IN VIVO.

Anne Plochowietz

, Diego

Duchi Llumigusin, Pawel Zawadzki, Afaf H. El-Sagheer, Tom Brown,

Achillefs N. Kapanidis

575-P

os

B

oard

B355

A DISORDER-BASED STRATEGY FOR THE INTRODUCTION OF

ALLOSTERIC, “HILL-TYPE” COOPERATIVITY INTO ARTIFICIAL

RECEPTORS.

Anna J. Simon

, Alexis Vallée-Bélisle, Francesco Ricci,

Herschel M. Watkins, Kevin W. Plaxco

576-P

os

B

oard

B356

STRUCTURE-FUNCTION RELATIONS AND RIGIDITY

PERCOLATION IN BIOPOLYMER NETWORKS IN LIVE TISSUE

UNDER SHEAR: BOVINE ARTICULAR CARTILAGE AS A MODEL

SYSTEM. Jesse L. Silverberg,

Moumita Das

, Aliyah R. Barrett, Poul B.

Petersen, Lawrence J. Bonassar, Itai Cohen

577-P

os

B

oard

B357

NUCLEAR DAMAGE IN HIGHLY CONSTRAINED MIGRATION:

FROM LAMINA DEFECTS TO DNA BREAKS.

Jerome Irianto

,

Avathamsa Athirasala, Rocky Diegmiller, Irena Ivanovska, Dennis E.

Discher

578-P

os

B

oard

B358

THE KINETICS OF NASCENT PROTEIN FOLDING UPON

RELEASE FROM THE RIBOSOME.

Rayna M. Addabbo

, Hon Nam

Lam, Brian Arnold, Silvia Cavagnero

579-P

os

B

oard

B359

DIFFUSION COEFFICIENT AS A FUNCTION OF MASS FOR

GLOBULAR BIOMOLECULES.

Michael J. Saxton

580-P

os

B

oard

B360

DEVELOPING A NANOCARRIER FOR TARGETED DELIVERY OF

CARDIO-PROTECTIVE AGENTS.

Nasr N. Alrabadi

, Jennifer I. Lai,

Chi L. Pham, Adrina F. Varda, Paul K. Witting, Margaret Sunde

581-P

os

B

oard

B361

THE NONRANDOM NATURE OF WEAK INTERACTIONS

BETWEEN PROTEINS AND BYSTANDER MACROMOLECULES

IN CELLULAR ENVIRONMENTS.

Sanbo Qin

, Huan-Xiang Zhou

582-P

os

B

oard

B362

international

travel awardee

A COMPUTATIONAL MODEL FOR E.COLI CYTOPLASM:

DIFFUSION AND HYDRODYNAMICS.

Sabeeha Hasnain

,

Christopher L. McClendon, Monica Tremont Hsu, Matthew P. Jacobson,

Pradipta Bandyopadhyay

Voltage-gated K Channels I

(Boards B363-B392)

583-P

os

B

oard

B363

MOVEMENTS OF THE KV2.1 AND KV6.4 S4 SEGMENTS IN

HETEROTETRAMERIC KV2.1/KV6.4 CHANNELS.

Elke Bocksteins

, Dirk J. Snyders, Miguel Holmgren

584-P

os

B

oard

B364

ION CHANNELS AND SALT BRIDGES: QUANTUM

CALCULATIONS SHOW UNUSUAL EFFECTS.

Alisher M. Kariev

,

Michael E. Green