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Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
1430-P
os
B
oard
B381
INVESTIGATIONS OF THE STRUCTURAL MECHANISM OF
MODULATION OF THE NMDA RECEPTOR.
Rita E. Sirrieh
, David
M. MacLean, Vasanthi Jayaraman
1431-P
os
B
oard
B382
EFFECTS OF EXTERNAL AND INTERNAL CA
2+
ON UNITARY
NMDA RECEPTOR PROPERTIES.
Gary J. Iacobucci
, Bruce A. Maki,
Gabriela K. Popescu
1432-P
os
B
oard
B383
NMDA RECEPTOR SMFRET STUDIES REVEAL ROLE OF
DYNAMICS OF THE AGONIST-BINDING DOMAIN IN
MEDIATING AGONIST EFFICACY.
Drew M. Dolino
, David R.
Cooper, Swarna S. Ramaswamy, Henriette Jaurich, Christy F. Landes,
Vasanthi Jayaraman
1433-P
os
B
oard
B384
REDUCED CURVATURE OF LIGAND-BINDING DOMAIN FREE
ENERGY SURFACE UNDERLIES PARTIAL AGONISM AT NMDA
RECEPTORS.
Jian Dai
, Huan-Xiang Zhou
1434-P
os
B
oard
B385
MEASUREMENT OF NR1/NR2B NMDA RECEPTOR
CURRENTS ON A MICROFLUIDIC BENCHTOP AUTOMATED
ELECTROPHYSIOLOGY PLATFORM. Jeffrey Webber, Craig McKay,
James Costantin
, Peter Miu
1435-P
os
B
oard
B386
THE STRUCTURAL BASIS OF NEGATIVE COOPERATIVITY
BETWEEN SUBUNITS OF THE NMDA RECEPTOR.
David M. MacLean
, Vasanthi Jayaraman
1436-P
os
B
oard
B387
SIMULATED CLOSING OF THE NMDA LIGAND-BINDING
DOMAIN.
Timothy S. Carpenter
, Felice C. Lightstone
1437-P
os
B
oard
B388
EFFECT OF PHOSPHORYLATION ON STRUCTURE OF
C-TERMINAL SEGMENT OF AMPA RECEPTOR.
Caitlin E. Nurik
,
David R. Cooper, Swarna S. Ramaswamy, Vasanthi Jayaraman
1438-P
os
B
oard
B389
CHARACTERIZATION OF A “HOTSPOT” IN THE AMPA
RECEPTOR ACTIVATION PATHWAY.
George B. Dawe
, Maria
Musgaard, Mark R. Aurousseau, Philip C. Biggin, Derek Bowie
1439-P
os
B
oard
B390
DYNAMICS OF THE CYTOPLASMIC REGION OF AN AMPA-
SUBTYPE GLUTAMATE RECEPTOR REVEALED BY STATE
DEPENDENT FRET.
Ljudmila Katchan
, Linda G. Zachariassen,
Anders S. Kristensen, Andrew J R Plested
1440-P
os
B
oard
B391
PARTIAL AGONIST BINDING REVEALS A UNIQUE
ARRANGEMENT OF AMPA LBDS.
Hector P. Salazar Garcia
, Clarissa
Ebli, Miriam Chebli, Andrew Plested
1441-P
os
B
oard
B392
STRUCTURAL MECHANISM OF GLUTAMATE RECEPTOR
ACTIVATION AND DESENSITIZATION.
Joel R. Meyerson
, Janesh
Kumar, Sagar Chittori, Prashant Rao, Jason Pierson, Alberto Bartesaghi,
Mark L. Mayer, Sriram Subramaniam
1442-P
os
B
oard
B393
LONG TIMESCALE SIMULATIONS OF LIGAND BINDING IN
GLUTAMATE RECEPTORS.
Alvin Yu
, Albert Lau
1443-P
os
B
oard
B394
CAN ACTIVATION AND DESENSITIZATION PROPERTIES OF
IGLURS BE PREDICTED AND UNDERSTOOD BY STUDYING
THE LBD DIMER DYNAMICS?
Maria Musgaard
, Bryan Daniels,
George B. Dawe, Mark Aurousseau, Derek Bowie, Philip C. Biggin
1444-P
os
B
oard
B395
FREE ENERGY LANDSCAPES FOR A KAINATE RECEPTOR
LIGAND-BINDING DOMAIN.
Tyler J. Wied
, Albert Y. Lau
1445-P
os
B
oard
B396
FUNCTIONAL COUPLING BETWEEN THE FINGER AND
THUMB DOMAINS OF ASIC1A.
Aram J. Krauson
, Marcelo D.
Carattino
1446-P
os
B
oard
B397
GATING MECHANISM AND MOVEMENTS IN ACID SENSING
ION CHANNEL 1A.
Swarna S. Ramaswamy
, David MacLean, Hugo
Sanabria, Vasanthi Jayaraman
1447-P
os
B
oard
B398
CONTROLLED ACTIVATION OF HETEROMERIC P2X
RECEPTORS BY ATP AND MAGNESIUM.
Emily Harnish
1448-P
os
B
oard
B399
QUANTITATIVE MEASURE OF CA
2+
CURRENT AND
PERMEABILITY IN ATP-GATED P2X7 RECEPTORS.
Xin Liang
,
Damien S.K. Samways, Terrance M. Egan
1449-P
os
B
oard
B400
ION ACCUMULATION AND DEPLETION IN PATCH CLAMP
EXPERIMENTS.
Gilman E. S. Toombes
, Mufeng Li, Shai D. Silberberg,
Kenton J. Swartz
1450-P
os
B
oard
B401
education
travel awardee
HEXADECANOL REVERSES ETHANOL INDUCED TADPOLE
ANESTHESIA AND RAISES CRITICAL TEMPERATURES IN
ISOLATED PLASMA MEMBRANE VESICLES.
Ellyn J. Gray
, Ann L.
Miller, Benjamin B. Machta, Sarah L. Veatch
1451-P
os
B
oard
B402
IL-4 TYPE 1 RECEPTOR SIGNALING UP-REGULATES
KCNN4
EXPRESSION, AND INCREASES THE K
CA
3.1 CURRENT AND
ITS CONTRIBUTION TO MIGRATION OF ALTERNATIVE-
ACTIVATED MICROGLIA. Lyanne Schlichter,
Roger Ferreira
, Starlee
Lively
1452-P
os
B
oard
B403
EQUILIBRIUM ION SELECTIVITY OF HUMAN TPC2 STUDIED
USING A PLASMA MEMBRANE-TARGETED HUMAN TPC2 AND
SPERMINE BLOCK.
Andy K. M. Lam
, Antony Galione
1453-P
os
B
oard
B404
MECHANISMS OF ACTIVATION OF SLO2.1 CHANNELS BY
INTRACELLULAR NA
+
.
Steven J. Thomson
, Michael C. Sanguinetti
1454-P
os
B
oard
B405
ELECTROPHYSIOLOGICAL CHARACTERIZATION OF
TMEM16A.
Andrea Bruggemann
, Markus Rapedius, Tom Götze,
Claudia Haarmann, Ilka Rinke, Marius Vogel, Timo Stengel, Johannes
Stiehler, Michael George, Niels Fertig, Torsten Ertongur-Fauth
1455-P
os
B
oard
B406
PHOTODYNAMIC MODIFICATION OF SEA URCHIN SPHCN
CHANNEL.
Vinay Kumar Idikuda
, Weihua Gao, Zhuocheng (Justin)
Su, Lei Zhou