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Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
1339-P
os
B
oard
B290
DYNAMICS OF CA
2+
-DEPENDENT REGULATION OF THE
CARDIAC NA
+
/CA
2+
EXCHANGER.
Lulu Chu
, Joseph L. Greenstein,
George S.B. Williams, Liron Boyman, Eric A. Legenzov, Brian M. Hagen,
W J. Lederer, Raimond L. Winslow
1340-P
os
B
oard
B291
NA-CA EXCHANGER CURRENT DURING THE CARDIAC
CYCLE IN INTACT PERFUSED MOUSE HEART. Josefina Ramos-
Franco,
Yuriana Aguilar-Sanchez
, Ariel L. Escobar
1341-P
os
B
oard
B292
STRUCTURAL AND FUNCTIONAL IMPACT OF AMINO ACID
SUBSTITUTION ON CALMODULIN BINDING IN CARDIAC
MYOCYTES.
Matthew D. McCoy
, Saleet Jafri, Iosif Vaisman
1342-P
os
B
oard
B293
THE FUNCTIONAL COMPLEX COMPOSED OF THE SODIUM/
BICARBONATE COTRANSPORTER AND THE SOLUBLE
ADENYLATE CYCLASE (SAC) MODULATES BASAL CARDIAC
CONTRACTILITY. María S. Espejo, María C. Ciancio, Alejandro
Orlowski, Verónica C. De Giusti,
Ernesto A. Aiello
1343-P
os
B
oard
B294
DMSO PROTECTS AGAINST STRESS-INDUCED SEALING
OF CARDIAC T-TUBULES.
Keita Uchida
, Ian Moench, Anatoli N.
Lopatin
1344-P
os
B
oard
B295
DUAL ROLE OF FUNCTIONALLY INTACT DYADIC
JUNCTIONS IN CARDIAC EXCITATION-CONTRACTION
COUPLING.
Prakash Subramanyam
, Donald D. Chang, Henry M.
Colecraft
1345-P
os
B
oard
B296
SUPER-RESOLUTION ANALYSIS OF THE DISTRIBUTION
OF RYR, CAV1.2 AND NCX WITHIN THE MAMMALIAN
COUPLON.
David R.L. Scriven
, Reza Tafteh, Keng C. Chou, Edwin
D.W. Moore
1346-P
os
B
oard
B297
SUPERRESOLUTION MICROSCOPE IMAGE
RECONSTRUCTION BY SPATIOTEMPORAL OBJECT
DECOMPOSITION AND ASSOCIATION: APPLICATION
IN RESOLVING T-TUBULE STRUCTURE IN SKELETAL
MUSCLE.
Mingzhai Sun
, Jiaqing Huang, Filiz Bunyak, Kristyn
Gumpper, Gejing De, Matthew Sermersheim, George Liu, Pei-Hui Lin,
Kannappan Palaniappan, Jianjie Ma
1347-P
os
B
oard
B298
VOLTAGE-GATED CALCIUM INFLUX CONTRIBUTES TO
SARCOPLASMIC RETICULUM CALCIUM LOADING IN
SKELETAL MUSCLE. Gaelle Robin,
Bruno Allard
1348-P
os
B
oard
B299
CONTRIBUTION OF L496-L500-W503 MOTIF OF DHPR-
β
1A
SUBUNIT TO SKELETAL-TYPE EC-COUPLING. Jose M. Eltit, Clara
Franzini-Armstrong,
Claudio F. Perez
1349-P
os
B
oard
B300
FRET-BASED STRUCTURAL ANALYSIS OF THE SKELETAL
MUSCLE DHPR USING BIARSENICAL LABELING.
Mohana Mahalingam
, Claudio F. Perez, James D. Fessenden
1350-P
os
B
oard
B301
DEPENDENCY OF CA
2+
ALTERNANS ON ION CHANNEL
LOCALIZATION IN HUMAN ATRIAL CELLS.
Kelly C. Chang
,
Natalia A. Trayanova
1351-P
os
B
oard
B302
AGEING CAUSES SEVERE ULTRA-STRUCTURAL
MODIFICATION OF CALCIUM RELEASE UNITS AND
MITOCHONDRIA IN CARDIOMYOCYTES. Laura d’Onofrio,
Alessia Di Fonso, Feliciano Protasi,
Simona Boncompagni
1352-P
os
B
oard
B303
THE EFFECT OF AGING ON CALCIUM TRANSIENTS IN RAT
CARDIOMYOCYTES: IMPACT OF NOX INHIBITION.
Daniel R. Gonzalez
, Guillermo B. Barrios
1353-P
os
B
oard
B304
OPTOGENETIC MANIPULATION OF CA
2+
TRANSIENTS
AND CONTRACTION IN A MATHEMATICAL MODEL OF
CARDIOMYOCYTE FUNCTION.
Yasser Aboelkassem
, Stuart G.
Campbell
1354-P
os
B
oard
B305
MG29/SYPL2 CONTRIBUTES TO DYSREGULATION OF LIPID
COMPOSITION AND STORE OPERATED CA
2+
ENTRY IN AGING
SKELETAL MUSCLE.
Julian A. Vallejo
, Liubov V. Gushchina, Sainath
Kotha, Leticia Brotto, Narasimham Parinandi, Noah Weisleder, Marco
Brotto
1355-P
os
B
oard
B306
DIFFERENTIAL ROLE OF CALSEQUESTRIN ISOFORMS ON
CALCIUM ENTRY IN SKELETAL MUSCLE FDB FIBRES.
Francesco Zorzato
, Barbara Mosca, Leda Beergamelli, Giorgia Valle,
Alessandra Nori, Susan Treves, Feliciano Protasi, Pomeo Volpe
1356-P
os
B
oard
B307
ELEVATION OF NO INCREASES CA
2+
ENTRY AND RESTING
CA
2+
AND NA
+
CONCENTRATIONS IN SKELETAL MUSCLE
CELLS.
Gaelle Robin
, Francisco Altamirano, Rui Zhang, Enrique
Jaimovich, Paul D. Allen, Jose R. Lopez
1357-P
os
B
oard
B308
A COMPARTMENT MODEL TO INVESTIGATE THE ROLES OF
SR MEMBRANE CHANNELS DURING E-C COUPLING.
Claudio Berti
, Michael Fill, Dirk Gillespie
1358-P
os
B
oard
B309
MODEL OF A PROPAGATING ACTION POTENTIAL (AP)
IN A TWITCH SKELETAL MUSCLE FIBER MOUNTED IN A
DOUBLE-VASELINE-GAP CHAMBER - CURRENTS INVOLVED
IN SHAPING THE AP. Fatou Touré, Gabor Gyurkovics, Cedric R.H.
Lamboley,
Paul C. Pape
1359-P
os
B
oard
B310
CAMKII-DEPENDENT PHOSPHORYLATION OF RYR2 CAUSES
DOMAIN UNZIPPING AND REDUCED CALMODULIN
BINDING, BUT DANTROLENE REVERSES THESE
EFFECTS.
Hitoshi Uchinoumi
, Yi Yang, Jose L. Puglisi, Ye Chen-Izu,
Razvan L. Cornea, Xander H. T. Wehrens, Donald M. Bers
1360-P
os
B
oard
B311
DETERMINATION OF THE JUNCTIONAL SPACE [CA
2+
] SET BY
RYANODINE RECEPTOR LEAK IN SLOW- AND FAST-TWITCH
MUSCLE FIBRES. Tanya R. Cully,
Bradley S. Launikonis
1361-P
os
B
oard
B312
EFFECT OF CALCIUM IN THE CARDIAC RYANODINE
RECEPTOR INTER-MOLECULAR CONTACTS.
Vanessa Cabra
,
Montserrat Samso