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84

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

1245-P

os

B

oard

B196

CYTOPLASMIC DOMAIN OF DENGUE VIRUS PROTEIN NS4A

PREFERENTIALLY BINDS HIGHLY CURVED MEMBRANES.

Yu-Fu Hung

, Melanie Schwarten, Silke Hoffmann, Dieter Willbold, Ella

H. Sklan, Bernd W. Koenig

1246-P

os

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oard

B197

PH TITRATION AND ACID ACTIVATION OF THE FULL-

LENGTH INFLUENZA A M2 PROTON CHANNEL IN LIPID

BILAYERS.

Yimin Miao

, Riqiang Fu, Huan-Xiang Zhou, Huajun Qin,

Timothy A. Cross

1247-P

os

B

oard

B198

PROBING STRUCTURE AND DYNAMICS OF EXTERNALIZED

TRANSMEMBRANE ALPHA HELICES OF S21 PINHOLIN

PROTEIN USING ELECTRON PARAMAGNETIC RESONANCE

SPECTROSCOPY.

Daniel Drew

1248-P

os

B

oard

B199

PROBING THE SECONDARY STRUCTURE OF MEMBRANE

PROTEIN USING BACTERIAL EXPRESSION SYSTEM AND

ELECTRON SPIN ECHO ENVELOPE MODULATION (ESEEM)

SPECTROSCOPY.

Rongfu Zhang

, Indra Sahu, Kaylee Gibson, Nefertiti

Muhammad, Avnika Bali, Raven Comer, Andrew Craig, Megan Dunagan,

Kunkun Wang, Carole Dabney-Smith, Gary Lorigan

1249-P

os

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oard

B200

STRUCTURE AND ACTIVITY OF THE OUTER MEMBRANE

PROTEIN AIL FROM YERSINIA PESTIS.

Yi Ding

, Lynn M. Fujimoto,

Yong Yao, Gregory V. Plano, Francesca M. Marassi

1250-P

os

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oard

B201

MECHANISMS OF MEMBRANE PROTEIN

CRYSTALLIZATION.

Anvar Samadzoda

, Amit Vaish, Anne Skaja

Robinson, Abraham Lenhoff

1251-P

os

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oard

B202

TRANSMEMBRANE-PEPTIDE STRUCTURE FORMATION

FROM COARSE-GRAINED SIMULATIONS.

Tristan Bereau

, Markus

Deserno

1252-P

os

B

oard

B203

OPENING THE LATERAL GATE OF THE RHOMBOID

PROTEASE COUPLES TO LIPID BINDING.

Ana Nicoleta Bondar

,

M. Joanne Lemieux

1253-P

os

B

oard

B204

HIGH RESOLUTION MODEL OF HDL WRAPPED WITH

TETRAFOIL APOA-I: A COARSE-GRAINED SIMULATION

STUDY.

Venkata Reddy Chirasani

, Sanjib Senapati

1254-P

os

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oard

B205

MEMBRANE ASSOCIATION OF SYNAPTOTAGMIN 7 C2A

DOMAIN BY MOLECULAR DYNAMICS SIMULATIONS.

Nara Lee Chon

, Jack Henderson, John Ryan Osterberg, Hanif Khan,

Nathalie Reuter, Jefferson Knight, Hai Lin

1255-P

os

B

oard

B206

INTERPLAY BETWEEN ELECTROSTATICS AND CATION-

PI INTERACTIONS GOVERNS THE SPECIFIC MEMBRANE

BINDING OF PHOSPHATIDYLINOSITOL-SPECIFIC

PHOSPHOLIPASE-C.

Hanif M. Khan

, Cedric Grauffel, Mary F.

Roberts, Anne Gershenson, Nathalie Reuter

1256-P

os

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oard

B207

MOLECULAR DETAILS OF THE MECHANISM OF PS

RECOGNITION BY TIM PROTEINS.

Javier L. Baylon

, Gregory T.

Tietjen, Ka Yee C. Lee, Erin J. Adams, Emad Tajkhorshid

1257-P

os

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oard

B208

ANOMALOUS DYNAMICS OF PLECKSTRIN HOMOLOGY

DOMAINS ON LIPID MEMBRANE SURFACES.

Eiji Yamamoto

,

Antreas C. Kalli, Takuma Akimoto, Kenji Yasuoka, Mark S. P. Sansom

1258-P

os

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oard

B209

MOLECULAR DYNAMICS SIMULATION STUDIES OF

INTERACTIONS OF E. COLI-K12 WITH OMPF IN OUTER

MEMBRANES: EFFECTS OF LPS STRUCTURES ON

MONOCLONAL ANTIBODIES BINDING.

Dhilon S. Patel

, Emilia

L. Wu, Phillip E. Klebba, Wonpil Im

1259-P

os

B

oard

B210

MODELLING PROTEIN-MICELLE SYSTEMS IN IMPLICIT

WATER.

Rodney E. Versace

, Themis Lazaridis

1260-P

os

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oard

B211

SIMULATIONS PREDICT 18:0-22:6 PHOSPHATIDYLSERINE

DRIVES

α

-SYNUCLEIN INTO THE LIQUID-DISORDERED

PHASE IN SYNAPTIC VESICLE LIPID COMPOSITION.

Benjamin E. Brummel

1261-P

os

B

oard

B212

THE STRUCTURE OF A MELITTIN STABILIZED TOROIDAL

PORE.

John M. Leveritt III

1262-P

os

B

oard

B213

MEMBRANOME: A DATABASE OF SINGLE-SPANNING

TRANSMEMBRANE PROTEINS.

Andrei L. Lomize

, Irina Pogozheva

1263-P

os

B

oard

B214

ROSETTA-MPDOCK: A NOVEL COMPUTATIONAL TOOL FOR

PROTEIN-PROTEIN DOCKING WITHIN THE MEMBRANE

BILAYER.

Julia Koehler Leman

, Rebecca F. Alford, Jeffrey J. Gray

1264-P

os

B

oard

B215

SUPER-RESOLUTION IMAGING AND REACTION MAPPING

OF P450 3A4 AND P450 REDUCTASE IN HETEROGENEOUS

BIOMIMETICS: STARRY NIGHT.

James A. Brozik

, Sara C.

Humphreys, Carlo Barnaba, Adam O. Barden, Jeffrey P. Jones

1265-P

os

B

oard

B216

APPLICATION OF LUMINESCENCE RESONANCE ENERGY

TRANSFER (LRET) FOR STUDY OF SUBSTRATE PEPTIDE

BINDING TO PGLB FROM N-LINKED GLYCOSYLATION

PATHWAY IN C. JEJUNI AND C. LARI.

Monika Musial-Siwek

,

Barbara Imperiali

1266-P

os

B

oard

B217

PROBING ENZYME-SUBSTRATE COMPLEX STRUCTURAL

DYNAMICS DURING INTRAMEMBRANE PROTEOLYSIS.

Jason W. Cooley

, Mia Brown, Renee D. JiJi

1267-P

os

B

oard

B218

TRACING LIPIDS AND THEIR ASSOCIATION WITH

KERATIN IN THE ADHESIVE GECKO SETAE BY NMR

SPECTROSCOPY.

Dharamdeep Jain

, Alyssa Stark, Peter Niewiarowski,

Toshikazu Miyoshi, Ali Dhinojwala

1268-P

os

B

oard

B219

INVESTIGATING THE STRUCTURAL DYNAMICS

TRANSITIONS OF HUMAN ADIPOCYTE FATTY ACID BINDING

PROTEIN BY NMR SPECTROSCOPY.

Kim N. Ha

, Youlin Xia, Yenchi

Tran, Adedolapo Ojoawo, Gianluigi Veglia, David A. Bernlohr

1269-P

os

B

oard

B220

SOLID STATE NMR STRUCTURAL STUDIES OF

ANTIMICROBIAL PEPTIDES LPCIN ANALOGS WITH

ENHANCED ACTIVITIES. Ji-Sun Kim, Ji-Ho Jeong,

Yongae Kim