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85

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

M

O

N

D

A

Y

1270-P

os

B

oard

B221

NMR-RESTRAINED STRUCTURE CALCULATIONS OF

MEMBRANE PROTEINS IN IMPLICIT LIPID BILAYER

MEMBRANES.

Ye Tian

, Charles Schwieters, Stanley Opella, Francesca

Marassi

1271-P

os

B

oard

B222

GLOBAL FOLD OF HUMAN CANNABINOID TYPE 2 RECEPTOR

PROBED BY SOLID-STATE NMR AND MOLECULAR DYNAMICS

SIMULATIONS. Tomohiro Kimura, Krishna Vukoti, Diane L. Lynch,

Dow P. Hurst, Alan Grossfield, Michael C. Pitman, Patricia H. Reggio,

Alexei A. Yeliseev,

Klaus Gawrisch

1272-P

os

B

oard

B223

BCL-2 FAMILY PROTEINS EFFECT ON MITOCHONDRIAL-

MIMICKING MEMBRANE STRUCTURE BY SOLID STATE

NMR.

Artur PG Dingeldein

, Martin Lidman, Sarka Pokorna, Martin

Hof, Anders Pedersen, Göran Karlsson, Gerhard Gröbner

Protein-Lipid Interactions II

(Boards B224-B248)

1273-P

os

B

oard

B224

DYNAMIC STUDIES OF THE TUMOUR SUPPRESSOR PROTIEN

PTEN BINDING TO MEMBRANES COMPOSED PI(4,5)P2 AND

VARIOUS ANIONIC LIPIDS.

Brittany M. Neumann

, Alonzo Ross,

Arne Gericke

1274-P

os

B

oard

B225

education

travel awardee

COMPUTATIONAL MODELING OF THE N-TERMINUS OF THE

HUMAN DOPAMINE TRANSPORTER (HDAT). George Khelashvili,

Milka Doktorova

, Michelle A. Sahai, Niklaus Johner, Lei Shi, Harel

Weinstein

1275-P

os

B

oard

B226

LOCALIZATION OF LIPIDS TO THE CAVITY AND

TRANSMEMBRANE DOMAIN OF ATP-BINDING CASSETTE

TRANSPORTER ABCB10, AS REVEALED BY MOLECULAR

DYNAMICS SIMULATIONS.

Hao Yu Chen

, Iwona Siuda, D. Peter

Tieleman

1276-P

os

B

oard

B227

INVESTIGATING SEC14 DOMAIN LIPID BINDING USING

STRUCTURAL MODELING.

Mwangala Akamandisa

, Amanda J.

Kedaigle, Mala L. Radhakrishnan, T. Kaye Peterman, Donald E. Elmore

1277-P

os

B

oard

B228

A MICROFLUIDIC DEVICE TO STUDY TRANSLOCATION

ACROSS LIPID MEMBRANES.

Victor Marin

, Roland Kieffer,

Jacqueline Enzlin, Marie-Eve Aubin-Tam

1278-P

os

B

oard

B229

BACKSCATTERING INTERFEROMETRY: SEEING MEMBRANE

PROTEINS IN A NEW LIGHT.

Janessa Gerhart

, Gabrielle Haddad-

Weiser, Amanda Kussrow, Darryl Bornhop, Robert Flowers, Damien

Thévenin

1279-P

os

B

oard

B230

MEMBRANE INSERTION DEPTH AND CURVATURE

SENSING.

Erin R. Tyndall

, Richard L. Gill Jr., Kumaran S.

Ramamurthi, Fang Tian

1280-P

os

B

oard

B231

CRYSTAL STRUCTURE OF THE BACTERIAL AMINOARABINOSE

TRANSFERASE ARNT.

Vasileios I. Petrou

, Oliver B. Clarke, Kathryn

M. Schultz, David Tomasek, Brian Kloss, Surajit Banerjee, Kanagalaghatta

R. Rajashankar, Candice S. Klug, Lawrence Shapiro, Filippo Mancia

1281-P

os

B

oard

B232

DISTINCT MEMBRANE ASSOCIATION MODES FACILITATE

CO-TRANSLATIONAL PROTEIN TARGETING.

Yu-Hsien Hwang

Fu

, Shu-ou Shan

1282-P

os

B

oard

B233

USING FLUORESCENT-LABELED NANODISCS TO STUDY

LIPID INTERACTIONS WITH YEAST CYTOCHROME C.

Harmen B. Steele

, Levi J. McClelland, Kristian T. Stipe, Michelle C.

Terwilliger, Bruce E. Bowler, J. B. Alexander Ross

1283-P

os

B

oard

B234

BIOPHYSICS OF

α

-SYNUCLEIN INDUCED MEMBRANE

REMODELLING.

Zheng Shi

, Elizabeth Rhoades, Tobias Baumgart

1284-P

os

B

oard

B235

ACETYLATION REGULATES THE INTERACTION OF

HUNTINGTIN WITH LIPID MEMBRANES: IMPLICATIONS

FOR HUNTINGTON DISEASE.

Maxmore Chaibva

, James R. Arndt,

Stephen J. Valentine, Justin Legleiter

1285-P

os

B

oard

B236

CHOLESTEROL MODULATES THE BINDING AND

SUBSEQUENT AGGREGATION OF HUNTINGTIN ON LIPID

BILAYERS.

Xiang Gao

, Maxmore Chaibva, Pranav Jain, Justin Legleiter

1286-P

os

B

oard

B237

SEQUENCE-INDEPENDENT SSDNA RELIEVES

PHOSPHOLAMBAN INHIBITION OF SERCA IN A LENGTH

DEPENDENT MANNER.

Kailey J. Soller

, Raffaello Verardi, Vitaly V.

Vostrikov, Neha Abrol, Seth L. Robia, Michael T. Bowser, Gianluigi Veglia

1287-P

os

B

oard

B238

SYSTEMATIC PERTURBATIONS OF MICELLE PROPERTIES TO

INVESTIGATE THE STABILIZATION OF MEMBRANE PROTEIN

STRUCTURE AND FUNCTION.

Ashton Brock

, Shelby Lipes, Linda

Columbus

1288-P

os

B

oard

B239

MODIFIED AMINOPHOSPHOLIPIDS STRONGLY ALTER THE

FUNCTION OF MITOCHONDRIAL MEMBRANE PROTEIN

UCP1.

Olga Jovanovic

, Nadine Burchardt, Lars Gille, Elena E. Pohl

1289-P

os

B

oard

B240

THE ROLE OF MEMBRANE CONTEXT IN THE

INTERACTION OF POLYGLUTAMINE PEPTIDES WITH LIPID

MEMBRANES.

Warren A. Campbell

, Karlina J. Kauffman, Justin

Legleiter, Shelli L. Frey

1290-P

os

B

oard

B241

PI(4,5)P2 LIPID BINDING INDUCES A REORIENTATION

OF FGF2 MOLECULES NEAR MEMBRANE SURFACE TO

FACILITATE THE UNCONVENTIONAL OLIGOMERIZATION-

DEPENDENT SECRETION PROCESS AS REVEALED BY A

COMBINED FTIR/NMR/X-RAY STUDY. Yh Tsao, Js Liu, Jh Kuo, Wn

Huang,

Wg Wu

1291-P

os

B

oard

B242

MEMBRANE SHAPE TRANSITION MEDIATED BY CURVATURE-

INDUCING PROTEINS, MEMBRANE TENSION, AND

MACROCROWDERS.

Zhiming Chen

, Zheng Shi, Tobias Baumgart

1292-P

os

B

oard

B243

ESTABLISHING THE SYNERGY OF FORCES GOVERNING TIM3

BINDING TO LIPID MEMBRANES.

Zhiliang Gong

, Greg T. Tietjen,

Daniel H. S. Kerr, J. Michael Henderson, Kathleen D. Cao, Nathaniel A.

Posner, Theodore L. Steck, Erin J. Adams, Ka Yee C. Lee