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90

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

Voltage-gated K Channels II

(Boards B333-B363)

1382-P

os

B

oard

B333

EFFECT OF AMITRIPTYLINE IN KV7.1/MINK CHANNEL.

Kathya Villatoro

, Sanchez-Chapula Jose Antonio, Tania Ferrer

1383-P

os

B

oard

B334

POLYUNSATURATED FATTY ACID ANALOGUES ACT ANTI-

ARRHYTHMIC ON THE CARDIAC IKS CHANNEL.

Sara I. Liin

,

Malin Silverå Ejneby, Rene Barro-Soria, Johan E. Larsson, Frida Starck

Härlin, Bo Hjorth Bentzen, Teija Parkkari, Nicole Schmitt, H. Peter

Larsson, Fredrik Elinder

1384-P

os

B

oard

B335

INTRACELLULAR CALCIUM ALTERS IKS AMPLITUDE AND

KINETICS IN RABBIT MYOCYTES.

Daniel C. Bartos

, Stefano

Morotti, Kenneth S. Ginsburg, Eleonora Grandi, Donald M. Bers

1385-P

os

B

oard

B336

BUILDING 3-D MODELS OF THE FULL-LENGTH IKS CNANNEL

USING COMPUTATIONAL TECHNIQUES.

Yu Xu

, Mei Zhang, Min

Jiang, Gea-Ny Tseng

1386-P

os

B

oard

B337

KCNE3 STABILIZES THE VOLTAGE SENSOR S4 OF KCNQ1

CHANNEL, KCNE1 UNCOUPLES S4 AND THE GATE.

Rene Barro-Soria

, Gary Peng, Kevin J. Sampson, Robert S. Kass, H.

Peter Larsson

1387-P

os

B

oard

B338

education

travel awardee

PHOSPHORYLATION OF KV7 CHANNELS REGULATES THEIR

PIP2 SENSITIVITY.

Fatma Asli Erdem

, Isabella Salzer, Wei-Qiang

Chen, Gert Lubec, Mark S. Shapiro, Stefan Boehm, Jae-Won Yang

1388-P

os

B

oard

B339

THE SUBFAMILY-SPECIFIC ASSEMBLY OF EAG AND ERG K

+

CHANNELS IS DETERMINED BY BOTH THE AMINO AND THE

CARBOXYL RECOGNITION DOMAINS. Ting-Feng Lin, Hao-Han

Wu, Chih-Yung Tang,

Chung-Jiuan Jeng

1389-P

os

B

oard

B340

DIRECT PREFERENTIAL INTERACTIONS BETWEEN HERG1A

AND HERG1B SUBUNITS: EVIDENCE FOR HERG1A-HERG1B

DIMERS.

Beth A. McNally

, Matthew C. Trudeau

1390-P

os

B

oard

B341

HOMOLOGOUS DOMAINS MEDIATE DISTINCT GATING

FUNCTIONS IN EAG VS. CYCLIC-NUCLEOTIDE GATED

CHANNELS.

Yaxian Zhao

, Colin H. Peters, Peter C. Ruben, Gail A.

Robertson

1391-P

os

B

oard

B342

AN EAG DOMAIN POLYPEPTIDE REGULATES THE

DEACTIVATION KINETICS OF THE HERG 1A-3.1 SPLICE

VARIANT LINKED TO SCHIZOPHRENIA.

Curtis D. Gallagher

,

Matthew C. Trudeau

1392-P

os

B

oard

B343

EAG K

+

CHANNEL BINDING TO CAMKII: STRUCTURAL AND

BIOCHEMICAL CHARACTERIZATION.

Artur F. Castro-Rodrigues

,

Fátima Fonseca, Carol A. Harley, João H. Morais-Cabral

1393-P

os

B

oard

B344

EXAMINING THE ROLE OF DIRECT CAMP-BINDING VERSUS

PKA-MEDIATED EFFECTS ON INTERACTIONS BETWEEN THE

CARDIAC POTASSIUM CHANNEL

α

-SUBUNIT PROTEINS HERG

AND KVLQT1. Yeon Joo Lee, Estelle Kim,

Louise E. Organ-Darling

1394-P

os

B

oard

B345

THE SUBPROTEOME OF MITOBKCA FROM

CARDIOMYOCYTES REVEALS NOVEL INSIGHTS INTO BK

CHANNEL FUNCTION AND PATHOLOGY.

Jin Zhang

, Zhu Zhang,

Ronghui Zhu, Stefani Enrico, Ligia Toro

1395-P

os

B

oard

B346

EFFECTS OF IK,ACH CHANNEL INHIBITOR TERTIAPIN-Q ON

RIGHT ATRIAL PREPARATIONS FROM PATIENTS IN SINUS

RHYTHM AND ATRIAL FIBRILLATION. Claire Poulet,

Sridharan Rajamani

, Ursula Ravens, Luiz Belardinelli

1396-P

os

B

oard

B347

MODULATION OF PANCREATIC ISLET ELECTROPHYSIOLOGY

AND INSULIN RELEASE BY POTASSIUM CHANNEL SUBUNIT

KVBETA2.

Peter Kilfoil

, Oleg A. Barski, Aruni Bhatnagar

1397-P

os

B

oard

B348

PHARMACOLOGICAL CONSEQUENCES OF PKC INHIBITION

ON KV1.5+KVBETA1.3 CHANNELS.

Alicia de la Cruz

, Alvaro

Macias, Angela Prieto, Diego A. Peraza, Michael M. Tamkun, Teresa

Gonzalez, Carmen Valenzuela

1398-P

os

B

oard

B349

INTERSUBUNIT INTERACTIONS CONTROL KIR CHANNEL

INACTIVATION.

William F. Borschel

, Shizhen Wang, Colin G.

Nichols

1399-P

os

B

oard

B350

INHIBITION OF HSP70 ENHANCES A-TYPE KV4 CURRENT BY

REDUCING DEGRADATION OF AUXILIARY KCHP4A.

Jingheng Zhou

, Yiquan Tang, Yanxin Lu, KeWei Wang

1400-P

os

B

oard

B351

DYNAMIC SUBUNIT STOICHIOMETRY OF KV4.3-KCHIP4A

CHANNEL COMPLEXES VISUALIZED BY SINGLE-MOLECULE

SUBUNIT COUNTING. Jingheng Zhou, Yiquan Tang, Liangyi Chen,

Zhuo Huang,

KeWei Wang

1401-P

os

B

oard

B352

THE N-TERMINAL EXTENSION OF KCHIP3 IS RESPONSIBLE

FOR KCHIP3-CALMODULIN COMPLEX FORMATION. Walter G.

Gonzalez,

Andres S. Arango

, Jaroslava Miksovska

1402-P

os

B

oard

B353

EXPLORING MOLECULAR MECHANISMS OF THE

FUNCTIONAL INTERACTION BETWEEN KV1.3 AND NAV

BETA1.

Tomoya Kubota

, Ana M. Correa, Francisco Bezanilla

1403-P

os

B

oard

B354

THE EFFECTS OF AUXILIARY SUBUNITS ON KV2.1

PHARMACOLOGY. Alissa J. Becerril, Autoosa Salari, Benjamin S. Vega,

Mirela Milescu

1404-P

os

B

oard

B355

CHARACTERIZATION OF BK CHANNELS CLONED FROM

MOUSE SINOATRIAL NODE CELLS.

Michael H. Lai

, Joshua P.

Whitt, Andrea L. Meredith

1405-P

os

B

oard

B356

REGULATION OF BK CURRENTS BY THE

β

2 SUBUNIT IN

MOUSE SUPRACHIASMATIC NUCLEUS.

Joshua P. Whitt

, Andrea

L. Meredith

1406-P

os

B

oard

B357

DIRECT MODULATION OF CALCIUM- AND VOLTAGE-

GATED POTASSIUM CHANNELS OF LARGE CONDUCTANCE

BY LEUKOTRIENES.

Anna N. Bukiya

, Jacob McMillan, Jianxi Liu,

Bangalore Shivakumar, Abby L. Parrill, Alex M. Dopico