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89
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
M
O
N
D
A
Y
1362-P
os
B
oard
B313
MALIGNANT HYPERTHERMIA SUSCEPTIBILITY MUTATION
CAV1.1 R174W DRAMATICALLY ALTERS RYR1 SINGLE
CHANNEL FUNCTION.
Wei Feng
, Yao Dong, Roger Bannister, Philip
Hopkins, Clara Franzini-Armstrong, Kurt Beam, Paul D. Allen, Isaac
Pessah
1363-P
os
B
oard
B314
EFFECTS OF MH AND CCD MUTATIONS IN THE CENTRAL
REGION ON RYR1 CHANNELS.
Takashi Murayama
, Nagomi
Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki,
Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, Takashi Sakurai
1364-P
os
B
oard
B315
CHARACTERIZATION OF DUAL MUTANT RYR1D-S100A1KO
MICE WITH DISRUPTED CAM AND S100A1 BINDING TO
CAMBD2 AND LACKING S100A1 EXPRESSION.
Erick O. Hernández-Ochoa
, Camilo Vanegas, Stephen J.P. Pratt, Richard
M. Lovering, Martin F. Schneider
1365-P
os
B
oard
B316
CORRELATION BETWEEN FKBP12/12.6 BOUND TO RYRS,
CHANNEL OPENING TO MAXIMAL OR SUBMAXIMAL
CONDUCTANCE LEVELS AND MYOPATHY. Gregory Steele, Philip
G. Board, Nicole A. Beard,
Angela F. Dulhunty
Cardiac, Smooth, and Skeletal Muscle
Electrophysiology II (Boards B317-B332)
1366-P
os
B
oard
B317
A COMPARISON OF ACUTELY ISOLATED HUMAN
VENTRICULAR MYOCYTES WITH STEM CELL DERIVED
CARDIOCYTES. Aaron D. Kaplan, Agnieszka Lis, Carlos Li, Lei Yang,
Michael J. Morales, Glenna C.L. Bett,
Randall L. Rasmusson
1367-P
os
B
oard
B318
AGING ALTERS CAMP SIGNALING AND MEMBRANE-
DELIMITED REGULATION OF I
F
IN SINOATRIAL
MYOCYTES.
Emily J. Sharpe
, Eric D. Larson, Catherine Proenza
1368-P
os
B
oard
B319
REGULATION OF ICA DURING SIMULATED ACUTE ISCHEMIA
IN DEVELOPING CARDIOMYOCYTES EXPOSED TO HYPOXIA
AND LOW PH.
Jose C. Fernandez-Morales
, Xiao-Hua Zhang, Hua
Wei, Lars Cleemann, Martin Morad
1369-P
os
B
oard
B320
NON-LINEAR REDUCTION OF ION CURRENTS IN CULTURED
CARDIAC MYOCYTES: CORRELATION WITH A LOSS OF
T-TUBULES? Tanya Zeina, Reuben T. Mathew, Erica Freund, Brian K.
Panama, Matthew Betzenhauser, Jacqueline A. Treat,
Jonathan M. Cordeiro
1370-P
os
B
oard
B321
T-TUBULES IN MYOCYTES OF INTACT DOG LEFT AND RIGHT
ATRIA. Gary L. Aistrup, Stephen Supple, Caleb Frank, Jasleen Singh,
Shannon Tai, Laura Chicos, Anne Zhao, William Marszalec, Rishi Arora,
AndrewWasserstrom
1371-P
os
B
oard
B322
CDO DEFICIENT MICE DISPLAY CARDIOMYOPATHY WITH
ALTERATIONS IN CONNEXINS.
Hyun-ji Kim
, Myong-Ho Jeong,
Young-Eun Leem, Jong-Sun Kang, Hana Cho
1372-P
os
B
oard
B323
LOSS OF PI3K-GAMMA SCAFFOLD FUNCTION CAUSES
SEVERE ELECTRICAL REMODELING IN MICE VENTRICULAR
MYOCYTES.
Riccardo Rizzetto
, Alexandra Jr Zahradnikova, Yueyi
Wang, Alessandra Ghigo, Rodolphe Fischmeister, Emilio Hirsch, Jean-
Pierre Benitah, Ana M. Gomez
1373-P
os
B
oard
B324
MASS SPECTROMETRY-BASED ANALYSIS OF THE PHOSPHO-
PROTEOME FOR CARDIAC DYSSYNCHRONY AND
RESYNCHRONIZATION THERAPY.
Jonathan A. Kirk
, Ronald J.
Holewinski, Vidya Venkatraman, Eric Grote, David A. Kass, Jennifer E.
Van Eyk
1374-P
os
B
oard
B325
MODULATION OF ACTION POTENTIAL ALTERNANS BY IKS
IN MYOCARDIAL INFARCTION. Bum-Rak Choi,
Tae Yun Kim
,
Mayara Grizotte-Lake, Jean Daley, Lorraine Schofield, Kamana Bist,
Joseph Yammine, Yukiko Kunitomo, Yichun Lu, Xuwen Peng, Zhilin Qu,
Gideon Koren
1375-P
os
B
oard
B326
A GUINEA PIG MODEL FOR HEART FAILURE-ASSOCIATED
SUDDEN CARDIAC DEATH.
Ting Liu
, Deeptankar Demazumder,
Brian O’Rourke
1376-P
os
B
oard
B327
IRON OVERLOAD PROMOTES ARRHYTHMIAS VIA ROS
PRODUCTION AND MITOCHONDRIAL MEMBRANE
POTENTIAL DEPOLARIZATION.
Richard Gordan
, Nadezhda
Fefelova, Judith Gwathmey, Lai-Hua Xie
1377-P
os
B
oard
B328
FRET MEASUREMENTS OF CAMP DYNAMICS IN HL1 CELLS
SUPPORT THE KEY ROLE OF CONSTITUTIVE AC ACTIVITY IN
CARDIAC PACEMAKING.
Evgeny Kobrinsky
, Kirill V. Tarasov, Yelena
S. Tarasova, Victor Maltsev, Steven J. Sollott, Edward G. Lakatta
1378-P
os
B
oard
B329
ABNORMALITIES IN TRANSMURAL VENTRICULAR
ELECTROPHYSIOLOGY IN A HETEROZYGOUS SCN5A
KNOCKOUT MOUSE MODEL REVEALED BY TWO-PHOTON
MICROSCOPY.
Allen Kelly
, Tomas O. Stølen, Karin Solvang-Garten,
Flavien Charpentier, Ulrik Wisløff, Godfrey L. Smith
1379-P
os
B
oard
B330
FEATURES OF OPTICAL MAPPING IN BLUE-GREEN AND NIR
LIGHTS IN RABBIT HEART.
Rūta Vosyliūtė
, Regina Mačianskienė,
Irma Martišienė, Antanas Navalinskas, Rimantas Treinys, Birutė Vaidelytė,
Jonas Jurevičius
1380-P
os
B
oard
B331
COMPREHENSIVE ANALYSIS OF BEHAVIORAL VARIABILITY
IN REAL AND SIMULATED POPULATIONS OF RABBIT LEFT
VENTRICULAR CARDIOMYOCYTES.
Ryan A. Devenyi
, Victor Z.
Rodriguez, Maria P. Hortigon-Vinagre, Godfrey L. Smith, Eric A. Sobie
1381-P
os
B
oard
B332
APPLICATION OF THE RIMARC ALGORITHM TO A LARGE
DATA SET OF ACTION POTENTIALS AND CLINICAL
PARAMETERS FOR RISK PREDICTION OF ATRIAL
FIBRILLATION.
Ursula Ravens
, Deniz Katircioglu-Öztürk, Erich
Wettwer, Claire Poulet, Simone Loose, Michael Knaut, Emre Oto, Ali
Oto, H. Altay Güvenir