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93
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
M
O
N
D
A
Y
1456-P
os
B
oard
B407
STUDYING THE INFLUENCE OF THE SUBUNIT
ARRANGEMENT ON THE FUNCTION OF
HETEROTETRAMERIC OLFACTORY CNG CHANNELS.
Jana Schirmeyer
, Vasilica Nache, Gunter Ehrlich, Thomas Zimmer, Klaus
Benndorf
1457-P
os
B
oard
B408
EFFECT OF LIGAND BINDING TO THE B1B SUBUNIT OF
OLFACTORY CNG CHANNELS.
Vasilica Nache
, Nisa Wongsamitkul,
Thomas Zimmer, Klaus Benndorf
1458-P
os
B
oard
B409
education
travel awardee
EXPLORATIONS OF LIPID EFFECTS IN CYCLIC
NUCLEOTIDE-GATED ION CHANNELS USING A NANODISC
PLATFORM.
Alexis Jaramillo Cartagena
, Crina Nimigean, Julia Kowal,
Henning Stahlberg
Cardiac Muscle Mechanics and Structure I
(Boards B410-B430)
1459-P
os
B
oard
B410
SELECTIVE ALPHA7 NICOTINIC RECEPTOR AGONIST
INCREASES CARDIAC FUNCTION IN ISOLATED MOUSE
HEARTS BY A NON-NICOTINIC MECHANISM.
Cyrus G. Takahashi
, Pooja Jagadish, Ashwin Jagadish, John P. Toscano,
Nazareno Paolocci, Donald B. Hoover
1460-P
os
B
oard
B411
LIFE-LONG TREATMENT WITH LATE SODIUM CURRENT
BLOCKER REDUCES MYOCARDIAL DYSFUNCTION AND
REMODELING IN A MOUSE MODEL OF HYPERTROPHIC
CARDIOMYOPATHY.
Francesca Gentile
, Raffaele Coppini, Cecilia
Ferrantini, Luca Mazzoni, Manuel J Pioner, Benedetta Tosi, Beatrice
Scellini, Alessandro Mugelli, Elisabetta Cerbai, Jill Tardif, Chiara Tesi,
Corrado Poggesi
1461-P
os
B
oard
B412
STAGE-DEPENDENT BENEFITS AND RISKS OF PIMOBENDAN
IN GENETIC DILATED CARDIOMYOPATHY MICE WITH
PROGRESSIVE HEART FAILURE.
Miki Nonaka
, Takashi Murayama,
Nagomi Kurebyashi, Lei Li, Yuan-Yuan Wang, Sachio Morimoto
1462-P
os
B
oard
B413
SAXAGLIPTIN PRESERVES CARDIOMYOCYTE FUNCTION AND
MORPHOLOGY IN AORTIC-BANDED MINI-SWINE.
Jessica A. Hiemstra
, Dong I. Lee, Ann K. Gibson, Melissa S. Cobb, Craig
A. Emter, Timothy L. Domeier
1463-P
os
B
oard
B414
DIRECT CARDIOTONIC ACTION OF QUERCETIN, A PLANT
FLAVONOID, THROUGH MECHANISM INDEPENDENT OF
ITS ANTI-OXIDATIVE ACTION.
Kengo Hayamizu
, Miki Nonaka,
Toshihiro Noma, Toshiyuki Sasaguri, Sachio Morimoto
1464-P
os
B
oard
B415
DCM MUTATION
ACTC
E361G CAUSES UNCOUPLING OF
MYOFIBRIL SENSITIVITY FROM TNI PHOSPHORYLATION
THAT CAN BE REVERSED BY EPIGALLOCATECHIN-3-
GALLATE.
Petr G. Vikhorev
, Weihua Song, Ross Wilkinson, O’Neal
Copeland, Michael A. Ferenczi, Steven B. Marston
1465-P
os
B
oard
B416
OBSCURIN MUTATIONS CAUSE HAPLOINSUFFICIENCY
AND ARE COMMON IN PATIENTS WITH FAMILIAL DILATED
CARDIOMYOPATHY (FDCM).
Steven Marston
, Ralph Knoll,
Cristobal dos Remedios, Alex Munster, O’neal Copeland, Cecile
Montgiraud
1466-P
os
B
oard
B417
DIFFERENTIAL INVOLVEMENT OF VARIOUS SOURCES
OF REACTIVE OXYGEN SPECIES IN THYROXIN-INDUCED
HEMODYNAMIC CHANGES AND CONTRACTILE
DYSFUNCTION OF THE HEART AND DIAPHRAGM
MUSCLES.
Mohammad T. Elnakish
, Eric J. Schultz, Rachel L.
Gearinger, Nancy S. Saad, Neha Rastogi, Amany A. E. Ahmed, Peter J.
Mohler, Paul M.L. Janssen
1467-P
os
B
oard
B418
MECHANICAL EFFECTS OF LATE NA-CURRENT BLOCKERS
IN HUMAN HYPERTROPHIC CARDIOMYOPATHY
MYOCARDIUM.
Cecilia Ferrantini
, Raffaele Coppini, Manuel
J. Pioner, Gentile Francesca, Tosi Benedetta, Luca Mazzoni, Luiz
Belardinelli, Chiara Tesi, Elisabetta Cerbai, Alessandro Mugelli, Corrado
Poggesi
1468-P
os
B
oard
B419
MYOCARDIAL DYSFUNCTION IN HYPERTROPHIC
CARDIOMYOPATHY: PRIMARY EFFECTS OF SARCOMERIC
MUTATIONS VERSUS SECONDARY EC-COUPLING
REMODELLING.
Raffaele Coppini
, Cecilia Ferrantini, Francesca
Gentile, Luca Mazzoni, Benedetta Tosi, Manuel J. Pioner, Beatrice
Scellini, Nicoletta Piroddi, Jil C. Tardiff, Chiara Tesi, Elisabetta Cerbai,
Corrado Poggesi
1469-P
os
B
oard
B420
R21C MUTATION IN CARDIAC TROPONIN I IMPOSES
DIFFERENCES IN THE DEGREE OF ORDER AND KINETICS
OF MYOSIN CROSS-BRIDGES OF LEFT AND RIGHT
VENTRICLES.
Divya Duggal
, Janhavi Nagwekar, Ryan Rich, Sangram
Raut, Rafal Fudala, Hriday Das, Zygmunt Gryczynski, Ignacy Gryczynski,
Julian Borejdo
1470-P
os
B
oard
B421
SPATIAL DISTRIBUTION OF ACTIN AND MECHANICAL
CYCLE OF MYOSIN ARE DIFFERENT IN RIGHT AND LEFT
VENTRICLES OF HEALTHY MOUSE HEARTS.
Janhavi Nagwekar
,
Divya Duggal, Ryan Rich, Sangram Raut, Rafal Fudala, Ignacy
Gryczynski, Zygmunt Gryczynski, Julian Borejdo
1471-P
os
B
oard
B422
UPREGULATION OF
α
1A-SUBTYPE ADRENERGIC SIGNALING
IS BENEFICIAL IN FAILING RIGHT VENTRICLE (RV).
Patrick M. Cowley
, Guanying Wang, Audrey N. Chang, David H.
Lovett, James T. Stull, Paul C. Simpson, Anthony J. Baker
1472-P
os
B
oard
B423
WORKLOOP CONTRACTIONS IN ISOLATED CARDIAC
MYOCYTES REFLECT IN VIVO PRESSURE-VOLUME
DYSFUNCTION IN RAT RIGHT HEART FAILURE.
Ewan D. Fowler
, Mark J. Drinkhill, Rob C. Wust, Michiel Helmes, Ger
J.M. Stienen, Derek S. Steele, Ed White
1473-P
os
B
oard
B424
USING OPTICAL COHERENCE TOMOGRAPHY TO MEASURE
DYNAMIC CHANGES IN THE GEOMETRY OF ISOLATED
CARDIAC TRABECULAE DURING A TWITCH.
Ming L. Cheuk
,
Alexander J. Anderson, June-Chiew Han, Bryan P. Ruddy, Marie-Louise
Ward, Denis S. Loiselle, Poul M. F. Nielsen, Andrew J. Taberner
1474-P
os
B
oard
B425
SYNCHRONIZATION MODEL OF SARCOMERES IN
CONTRACTING CARDIOMYOCYTES.
Virginijus Barzda
, Nicole
Prent, Masood Samim, Sara Wegener, Richard Cisek