SimultaneousDetermination of SevenWater SolubleVitamins inProducts byLC-MS/MS
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Table 4. Method precision cont’d
FolicAcid
PantothenicAcid
Niacin
SMPRCriteria
≤7%
≤5%
≤6%^^
LOTno.:
Average*
Repeatability
%RSD
IP
Average*
Repeatability
%RSD
IP
Average*
Repeatability
%RSD
IP
Infant formulaPWDSoy
Based**
E29JVLV
17.21
3.7
4.9%
487.7
2.8
3.8%
969.2
2.0
2.4%
Adult Nutritional PWDmilk
protein based**
11750017V3
27.58
1.9
4.2%
294.5
1.8
3.1%
667.1
1.4
3.2%
Infant FormulaPWDPartially
hydrolyzed soybased**
117257651Z
18.68
4.6
5.1%
428.2
2.1
2.3%
778.3
1.4
2.8%
Infant FormulaPWDPartially
hydrolyzedmilkbased**
1172572116
15.86
3.4
5.2%
405.7
1.5
1.6%
701.5
1.7
2.5%
SRM 1849a**
CLC10-b
25.52
3.9
4.9%
761.6
1.2
2.1%
1110
2.3
2.7%
Adult nutritional highprotein**
00414RF00
5.75
4.2
5.1%
179.7
1.3
3.9%
311.3
1.5
2.7%
Adult nutritional RTF high fat**
00406RF00
6.60
4.6
5.3%
226.7
5.4
4.4%
418.3
2.5
2.4%
ChildRTF^
NA
33.28
5.4
4.6
1471
1.1
2.0
1393
1.5
2.7
Infant Elemental PWD^
NA
48.07
2.8
4.1
1202
1.2
4.9
2435
1.8
2.6
Adult LowFat RTF^
NA
58.01
1.5
2.5
1792
1.1
2.9
3582
1.6
2.6
Adult HighFat RTF^
NA
127.2
3.1
4.0
2293
1.5
2.2
4891
3.0
5.0
* µg/100 gproduct as ready to feed
** n=12, duplicate analysis on 6days, single analyst, single instrument
^ n-16, duplicate analysis on 8days, two analysts, two instruments as part of internal SLV effort
^^ AnSMPR has not beenpublished. For purposes of evaluation the biotin criteriawill be used.
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