SimultaneousDetermination of SevenWater SolubleVitamins inProducts byLC-MS/MS
Page
8
of
20
Table 4. Method precision cont’d
Pyridoxine
Riboflavin
Thiamine
SMPRCriteria
≤6%^^
≤6%^^
≤6%^^
LOTno.:
Average*
Repeatability
%RSD
Average*
Repeatability
%RSD
Average*
Repeatability
%RSD
Infant formulaPWDSoyBased**
E29JVLV
64.49
1.3
3.3%
205.9
1.1
1.5%
166.3
8.1
8.5%
Adult Nutritional PWDmilkprotein
based**
11750017V3
229.0
1.5
1.8%
66.25
1.2
1.1%
64.65
3.9
5.6%
Infant FormulaPWDPartially
hydrolyzed soybased**
117257651Z
61.06
2.4
3.6%
103.9
0.9
1.3%
115.0
4.1
3.8%
Infant FormulaPWDPartially
hydrolyzedmilkbased**
1172572116
52.11
1.5
3.1%
137.1
1.4
2.5%
101.0
3.6
3.8%
SRM 1849a**
CLC10-b
147.8
1.4
1.7%
223.0
0.9
1.2%
188.1
5.8
5.0%
Adult nutritional highprotein**
00414RF00
40.27
3.2
3.3%
39.17
0.8
1.3%
27.85
3.2
3.4%
Adult nutritional RTF high fat**
00406RF00
50.24
3.6
3.5%
47.10
1.3
1.4%
25.91
3.4
3.5%
ChildRTF^
NA
380.8
1.4
2.1
384.0
1.2
2.1
299.3
1.1
2.9
Infant Elemental PWD^
NA
113.6
1.6
2.8
147.7
1.2
2.0
331.0
1.9
3.3
Adult LowFat RTF^
NA
435.5
0.9
1.6
432.8
0.5
1.8
314.1
1.4
3.2
Adult HighFat RTF^
NA
1114
1.3
1.6
423.1
1.3
2.1
248.6
1.5
2.8
* µg/100 gproduct as ready to feed
** n=12, duplicate analysis on 6days, single analyst, single instrument
^ n-16, duplicate analysis on 8days, two analysts, two instruments as part of internal SLV effort
^^ AnSMPR has not beenpublished. For purposes of evaluation the biotin criteriawill be used.
BIO-03
FORWORKINGGROUP/ERPUSEONLY
DONOTDISTRIBUTE
