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EGFR inhibition + RCT in HNSCC
•
Benefit with
chemotherapy
?
Ang KK, J Clin Oncol. 2011;29, ASTRO
Local-Regional Control
Radiotherapy
±
cddp
±
Panitumumab
Giralt et al., 2013
•
Oral cavity, oropharynx, hypopharynx and larynx
•
Stade III and IV SCC
•
IMRT and 3D-CRT
Concert 1: RT + cddp ± panitumumab
Concert 2: RT + cddp >< RT + panitumumab