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Triggers of immunogenic cell death

07.09.17

ESTRO SBRT COURSE 2017 - Matthias Guckenberger

23

• Radiation, photodynamic therapy and high hydrostatic pressure

only documented physical triggers of ICD (not freezing or boiling)

Galluzzi Nature Reviews 2016

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Micro-enviroment

07.09.17

ESTRO SBRT COURSE 2017 - Matthias Guckenberger

24

Ø

Radiation induces vascular, stromal and immunological

changes in the tumor microenviroment

Barker Nature Reviews Cancer 2015